Overview

  • Product name
  • Description
    Rabbit polyclonal to SPHK1
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human SPHK1 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH).

  • Positive control
    • Adrenal tissue (pheochromocytes).

Properties

Applications

Our Abpromise guarantee covers the use of ab61148 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 10 µg/ml.

Target

  • Function
    Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra-and extracellular functions. Also acts on D-erythro-sphingosine and to a lesser extent sphinganine, but not other lipids, such as D,L-threo-dihydrosphingosine, N,N-dimethylsphingosine, diacylglycerol, ceramide, or phosphatidylinositol.
  • Tissue specificity
    Widely expressed with highest levels in adult liver, kidney, heart and skeletal muscle.
  • Sequence similarities
    Contains 1 DAGKc domain.
  • Information by UniProt
  • Database links
  • Alternative names
    • SK 1 antibody
    • SK1 antibody
    • Sphingosine kinase 1 antibody
    • SPHK 1 antibody
    • SPHK antibody
    • Sphk1 antibody
    • SPHK1_HUMAN antibody
    • SPK antibody
    • SPK 1 antibody
    see all

Images

  • Ab61148 (10ug/ml) staining human SPHK1 in human adrenal tissue (pheochromocytes) by immunohistochemistry using formalin fixed, paraffin embedded tissue.

References

ab61148 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab61148.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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