Overview

  • Product name
  • Description
    Rabbit polyclonal to SPINK1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Rat
  • Immunogen

    Synthetic peptide within Rat SPINK1 aa 66-79 conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Sequence:

    KFGTSIHIQRRGTC


    Database link: P09655

  • Positive control
    • Rat pancreas tissue.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.09% Sodium azide
    Constituents: 50% Glycerol, 0.01% BSA
  • Concentration information loading...
  • Purity
    Protein A purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab203579 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500.

When using a fluorescent probe the recommended dilution is 1/50 – 1/200

Target

  • Function
    Serine protease inhibitor which exhibits anti-trypsin activity (PubMed:7142173). In the pancreas, protects against trypsin-catalyzed premature activation of zymogens.
    In the male reproductive tract, binds to sperm heads where it modulates sperm capacitance by inhibiting calcium uptake and nitrogen oxide (NO) production.
  • Involvement in disease
    Pancreatitis, hereditary
    Tropical calcific pancreatitis
  • Sequence similarities
    Contains 1 Kazal-like domain.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • ISK1_HUMAN antibody
    • Pancreatic secretory trypsin inhibitor antibody
    • Pancreatic serine protease inhibitor Kazal antibody
    • PCTT antibody
    • PSTI antibody
    • Serine protease inhibitor Kazal type 1 antibody
    • Serine protease inhibitor Kazal-type 1 antibody
    • Spink 3 antibody
    • SPINK1 antibody
    • Spink3 antibody
    • TaTI antibody
    • TCP antibody
    • Tumor associated trypsin inhibitor antibody
    • Tumor-associated trypsin inhibitor antibody
    see all

Images

  • Immunohistochemical analysis of formalin/PFA-fixed paraffin-embedded rat pancreas tissue sections labeling SPINK1 with ab203579 at a 1/200 dilution, followed by conjugation to the secondary antibody and DAB staining.

References

ab203579 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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