Recombinant
RabMAb

Anti-SPINK1 antibody [EPR12696(2)] (ab183034)

Overview

  • Product name
    Anti-SPINK1 antibody [EPR12696(2)]
    See all SPINK1 primary antibodies
  • Description
    Rabbit monoclonal [EPR12696(2)] to SPINK1
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human SPINK1 aa 50 to the C-terminus. The exact sequence is proprietary.
    Database link: P00995

  • Positive control
    • Human pancreas lysate; Human pancreas tissue.
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.01% Sodium azide
    Constituents: 59% PBS, 40% Glycerol, 0.05% BSA
  • Concentration information loading...
  • Purity
    Protein A purified
  • Clonality
    Monoclonal
  • Clone number
    EPR12696(2)
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab183034 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/4000.
WB 1/10000 - 1/50000. Detects a band of approximately 9 kDa (predicted molecular weight: 9 kDa).

Target

  • Function
    Serine protease inhibitor which exhibits anti-trypsin activity (PubMed:7142173). In the pancreas, protects against trypsin-catalyzed premature activation of zymogens.
    In the male reproductive tract, binds to sperm heads where it modulates sperm capacitance by inhibiting calcium uptake and nitrogen oxide (NO) production.
  • Involvement in disease
    Pancreatitis, hereditary
    Tropical calcific pancreatitis
  • Sequence similarities
    Contains 1 Kazal-like domain.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • ISK1_HUMAN antibody
    • Pancreatic secretory trypsin inhibitor antibody
    • Pancreatic serine protease inhibitor Kazal antibody
    • PCTT antibody
    • PSTI antibody
    • Serine protease inhibitor Kazal type 1 antibody
    • Serine protease inhibitor Kazal-type 1 antibody
    • Spink 3 antibody
    • SPINK1 antibody
    • Spink3 antibody
    • TaTI antibody
    • TCP antibody
    • Tumor associated trypsin inhibitor antibody
    • Tumor-associated trypsin inhibitor antibody
    see all

Images

  • Immunohistochemical analysis of Paraffin-embedded Human pancreas tissue labeling SPINK1 with ab183034 at 1/4000 dilution followed by pre-diluted HRP-conjugated secondary antibody and counter-stained with Hematoxylin.

  • Anti-SPINK1 antibody [EPR12696(2)] (ab183034) at 1/50000 dilution + Human pancreas lysate at 20 µg

    Secondary
    Goat Anti-rabbit IgG HRP at 1/1000 dilution

    Predicted band size: 9 kDa

References

ab183034 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab183034.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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