Overview

  • Product nameAnti-SPIRE1 antibody
    See all SPIRE1 primary antibodies
  • Description
    Mouse monoclonal to SPIRE1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 482-584 of Human SPIRE1

Properties

Applications

Our Abpromise guarantee covers the use of ab57463 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionActs as a actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in vesicle transport processes providing a novel link between actin organization and intracellular transport.
    • Sequence similaritiesBelongs to the spire family.
      Contains 1 KIND domain.
      Contains 2 WH2 domains.
    • DomainBinds to actin monomers via the WH2 domain.
      The Spir-box targets binding to intracellular membrane structures.
    • Cellular localizationCytoplasm > cytoskeleton. Cytoplasm > perinuclear region. Punctate spots in perinuclear region and cytoplasm, co-localised with Rab11.
    • Information by UniProt
    • Database links
    • Alternative names
      • KIAA1135 antibody
      • MGC150621 antibody
      • MGC150622 antibody
      • Protein spire homolog 1 antibody
      • Spir 1 antibody
      • Spir-1 antibody
      • Spir1 antibody
      • SPIR1_HUMAN antibody
      • SPIRE 1 antibody
      • Spire homolog 1 antibody
      • spire1 antibody
      see all

    Anti-SPIRE1 antibody images

    • Western blot against tagged recombinant protein immunogen using ab57463 SPIRE1 antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa

    References for Anti-SPIRE1 antibody (ab57463)

    ab57463 has not yet been referenced specifically in any publications.

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    Thank you for taking time to complete our questionnaire. I am sorry to hear that this antibody is not providing satisfactory results with Rat samples.
    As shown on the product datasheet (www.abcam.com/ab57463) this antibody has not been tested with...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"