Anti-splicing factor 1 (phospho S82) antibody (ab59242)

Overview

  • Product nameAnti-splicing factor 1 (phospho S82) antibody
    See all splicing factor 1 primary antibodies
  • Description
    Rabbit polyclonal to splicing factor 1 (phospho S82)
  • SpecificityThis antibody detects endogenous levels of splicing factor 1 (SF1) only when phosphorylated at serine 82.
  • Tested applicationsSuitable for: ELISA, IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic phosphopeptide derived from human splicing factor 1 around the phosphorylation site of serine 82 (SPSPPE).

  • Positive control
    • Human brain tissue, A549 cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab59242 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/5000.
IHC-P Use at an assay dependent concentration.
ICC/IF Use at an assay dependent concentration.

Target

  • RelevanceSF1 contains 1 KH domain, 1 CCHC type zinc finger, a nuclear transport domain and glutamine and proline rich regions. It is necessary for the ATP dependent first step of spliceosome assembly and binds to the intron branch point sequence (BPS) 5' UACUAAC 3' of the pre mRNA. It may act as transcription repressor. There are 6 named isoforms produced by alternative splicing.
  • Cellular localizationNuclear
  • Database links
  • Alternative names
    • BBP antibody
    • D11S636 antibody
    • Mammalian branch point binding protein mBBP antibody
    • OTTHUMP00000069749 antibody
    • OTTHUMP00000069750 antibody
    • OTTHUMP00000069752 antibody
    • Splicing factor 1 antibody
    • Transcription factor ZFM1 antibody
    • ZFM1 antibody
    • Zinc finger gene in MEN1 locus antibody
    • Zinc finger protein 162 antibody
    • ZNF162 antibody
    see all

Anti-splicing factor 1 (phospho S82) antibody images

  • ab59242 at 1/50 dilution staining splicing factor 1 in human brain by Immunohistochemistry, Paraffin embedded tissue, in the absence or presence of the immunizing peptide.

References for Anti-splicing factor 1 (phospho S82) antibody (ab59242)

ab59242 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"