Anti-Sprouty 4 antibody - C-terminal (ab82298)

Overview

  • Product name
    Anti-Sprouty 4 antibody - C-terminal
    See all Sprouty 4 primary antibodies
  • Description
    Rabbit polyclonal to Sprouty 4 - C-terminal
  • Tested applications
    Suitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    KLH conjugated synthetic peptide selected from the C-terminal region of human Sprouty 4.

  • Positive control
    • Sk-Br-3 cell line lysate.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab82298 is purified through a protein A column, followed by peptide affinity purification.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab82298 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/1000.
WB 1/50 - 1/100. Predicted molecular weight: 32 kDa.

Target

  • Function
    Suppresses the insulin receptor and EGFR-transduced MAPK signaling pathway, but does not inhibit MAPK activation by a constitutively active mutant Ras. Probably impairs the formation of GTP-Ras.
  • Sequence similarities
    Belongs to the sprouty family.
    Contains 1 SPR (sprouty) domain.
  • Domain
    The Cys-rich domain is responsible for the localization of the protein to the membrane ruffles.
  • Cellular localization
    Cytoplasm. Cell projection > ruffle membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Protein sprouty homolog 4 antibody
    • Sprouty homolog 4 antibody
    • sprouty homolog 4 (Drosophila) antibody
    • SPRY 4 antibody
    • Spry-4 antibody
    • Spry4 antibody
    • SPY4_HUMAN antibody
    see all

Images

References

ab82298 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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