Overview

  • Product name
    Anti-SPRR4 antibody
  • Description
    Rabbit polyclonal to SPRR4
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human SPRR4 aa 32-79.
    Sequence:

    VKCQETCAPKTKDPCAPQVKKQCPPKGTIIPAQQKCPSAQQASKSKQK


    Database link: Q96PI1

  • Positive control
    • Human vulva/anal skin

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    pH: 7.2
    Preservative: 0.02% Sodium azide
    Constituents: 40% Glycerol, 59% PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab185511 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/500 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Cross-linked envelope protein of keratinocytes. Involved in UV-induced cornification.
  • Sequence similarities
    Belongs to the cornifin (SPRR) family.
  • Post-translational
    modifications
    Cross-linked to membrane proteins by transglutaminase.
  • Cellular localization
    Cytoplasm. Cytoplasm > cell cortex. Translocates to the cell periphery of keratinocytes and is integrated into both rigid and fragile cornified envelopes.
  • Information by UniProt
  • Database links
  • Alternative names
    • Small proline-rich protein 4 antibody
    • SPRR4 antibody
    • SPRR4_HUMAN antibody

Images

  • Immunohistochemical staining of formalin fixed, paraffin embedded Human vulva/anal skin labeling SPRR4 using ab188511 at a 1/500 dilution.

References

ab185511 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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