Overview

  • Product nameAnti-SPTBN1 antibody
    See all SPTBN1 primary antibodies
  • Description
    Rabbit polyclonal to SPTBN1
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to a region between residues 2150 and 2200 of Human SPTBN1 (NP_003119.2).

  • Positive control
    • Human prostate adenocarcinoma.

Properties

Applications

Our Abpromise guarantee covers the use of ab84498 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notesIHC-P: 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionFodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.
    • Tissue specificityIsoform 2 is present in brain, lung and kidney (at protein level).
    • Sequence similaritiesBelongs to the spectrin family.
      Contains 2 CH (calponin-homology) domains.
      Contains 1 PH domain.
      Contains 17 spectrin repeats.
    • Post-translational
      modifications
      Isoform 2 is phosphorylated on Ser-8 and Ser-10.
    • Cellular localizationCell membrane and Cytoplasm > cytoskeleton. Cytoplasm > myofibril > sarcomere > M line. Colocalizes with ANK2 in a distinct intracellular compartment of neonatal cardiomyocytes.
    • Information by UniProt
    • Database links
    • Alternative names
      • Beta G spectrin antibody
      • Beta II spectrin antibody
      • Beta spectrin 2 antibody
      • Beta spectrin II antibody
      • Beta-II spectrin antibody
      • betaSpII antibody
      • brain 1 antibody
      • ELF antibody
      • Embryonic liver beta fodrin antibody
      • Fodrin beta chain antibody
      • non-erythroid beta chain 1 antibody
      • Spectrin antibody
      • Spectrin beta chain antibody
      • Spectrin, beta, non erythrocytic 1 antibody
      • Spectrin, non erythroid beta chain 1 antibody
      • SPTB2 antibody
      • SPTB2_HUMAN antibody
      • SPTBN1 antibody
      see all

    Anti-SPTBN1 antibody images

    • ab84498, at 1/250 dilution, staining SPTBN1 in formalin-fixed, paraffin-embedded human prostate adenocarcinoma by Immunohistochemistry, using DAB staining.

    References for Anti-SPTBN1 antibody (ab84498)

    ab84498 has not yet been referenced specifically in any publications.

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