Overview

  • Product name
    Anti-Squalene Epoxidase antibody
    See all Squalene Epoxidase primary antibodies
  • Description
    Mouse polyclonal to Squalene Epoxidase
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length protein, corresponding to amino acids 1-574 of Human Squalene Epoxidase

Properties

Applications

Our Abpromise guarantee covers the use of ab67479 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 55 kDa (predicted molecular weight: 64 kDa).

Target

  • Function
    Catalyzes the first oxygenation step in sterol biosynthesis and is suggested to be one of the rate-limiting enzymes in this pathway.
  • Pathway
    Terpene metabolism; lanosterol biosynthesis; lanosterol from farnesyl diphosphate: step 2/3.
  • Sequence similarities
    Belongs to the squalene monooxygenase family.
  • Cellular localization
    Microsome membrane. Endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • ERG1 antibody
    • ERG1_HUMAN antibody
    • SE antibody
    • SQLE antibody
    • Squalene epoxidase antibody
    • Squalene monooxygenase antibody
    see all

Images

  • All lanes : Anti-Squalene Epoxidase antibody (ab67479) at 1/500 dilution

    Lane 1 : Squalene Epoxidase transfected 293T cell lysate
    Lane 2 : non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP conjugated at 1/2500 dilution

    Predicted band size : 64 kDa
    Observed band size : 55 kDa (why is the actual band size different from the predicted?)

References

ab67479 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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