Overview

  • Product nameAnti-SRA1 antibody
    See all SRA1 primary antibodies
  • Description
    Rabbit polyclonal to SRA1
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chimpanzee, Rhesus monkey, Gorilla
  • Immunogen

    Synthetic peptide corresponding to a region between residues 50 and 100 of human SRA1 (NP_001030312.1).

  • Positive control
    • Human metastatic lymph node and human breast carcinoma tissues.

Properties

Applications

Our Abpromise guarantee covers the use of ab84388 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notesIHC-P: 1/100 - 1/500.
    Epitope exposure with citrate buffer will enhance staining.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionFunctional RNA which acts as a transcriptional coactivator that selectively enhances steroid receptor-mediated transactivation ligand-independently through a mechanism involving the modulating N-terminal domain (AF-1) of steroid receptors. Also mediates transcriptional coactivation of steroid receptors ligand-dependently through the steroid-binding domain (AF-2). Enhances cellular proliferation and differentiation and promotes apoptosis in vivo. May play a role in tumorigenesis.
    • Tissue specificityHighly expressed in liver and skeletal muscle and to a lesser extent in brain. Also expressed in both normal and tumorigenic breast epithelial cell lines. Significantly up-regulated in human tumors of the breast, ovary, and uterus.
    • Sequence similaritiesBelongs to the SRA1 family.
    • Cellular localizationNucleus. Cytoplasm.
    • Information by UniProt
    • Database links
    • Alternative names
      • MGC87674 antibody
      • PP7684 antibody
      • SR A1 antibody
      • SRA antibody
      • SRA1 antibody
      • SRA1_HUMAN antibody
      • SRAP antibody
      • Steroid receptor coactivator antibody
      • Steroid receptor RNA activator 1 (complexes with NCOA1) antibody
      • Steroid receptor RNA activator 1 antibody
      • Steroid receptor RNA activator protein antibody
      • STRAA1 antibody
      see all

    Anti-SRA1 antibody images

    • ab84388, at a 1/100 dilution, staining SRA1 in formalin fixed, paraffin embedded human metastatic lymph node tissue by Immunohistochemistry.
      Detection: DAB staining.
    • ab84388, at a 1/100 dilution, staining SRA1 in formalin fixed, paraffin embedded human breast carcinoma tissue by Immunohistochemistry.
      Detection: DAB staining.

    References for Anti-SRA1 antibody (ab84388)

    This product has been referenced in:
    • Lee J  et al. The liver is populated by a broad spectrum of markers for macrophages. In alcoholic hepatitis the macrophages are M1 and M2. Exp Mol Pathol N/A:N/A (2013). IHC-P ; Human . Read more (PubMed: 24145004) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"