This fast track antibody is not yet fully characterized. It is subject to these terms and conditions

Overview

  • Product nameAnti-SRCAP antibody
  • Description
    Goat polyclonal to SRCAP

    This product is a fast track antibody. It has been affinity purified and shows high titre values against the immunizing peptide by ELISA. Read the terms of use »

  • Species reactivity

    Predicted to work with: Mouse, Rat, Dog, Human
  • Immunogen

    Synthetic peptide:

    C-DEAQNIKNFKSQR

    , corresponding to internal sequence amino acids 746-758 of Human SRCAP (NP_006653.2).

Properties

Applications

Fast track antibodies constitute a diverse group of products that have been released to accelerate your research, but are not yet fully characterized. They have all been affinity purified and show high titre values against the immunizing peptide (by ELISA). Fast track terms of use

Application Abreviews Notes
WB Use at an assay dependent dilution. Predicted molecular weight: 344 kDa. Preliminary experiments in lysates of cell lines K562 and MOLT4 gave no specific signal but low background (at antibody concentration up to 1µg/ml).

Target

  • RelevanceCatalytic component of the SRCAP complex which mediates the ATP-dependent exchange of histone H2AZ/H2B dimers for nucleosomal H2A/H2B, leading to transcriptional regulation of selected genes by chromatin remodeling. Acts as a coactivator for CREB-mediated transcription, steroid receptor-mediated transcription, and Notch-mediated transcription (from SwissProt).
  • Cellular localizationNuclear
  • Database links
  • Alternative names
    • domino homolog 2 antibody
    • DOMO1 antibody
    • EAF1 antibody
    • FLHS antibody
    • Helicase SRCAP antibody
    • KIAA0309 antibody
    • Snf2 related CBP activator protein antibody
    • Swi2/Snf2-related ATPase homolog, domino homolog 1 antibody
    • SWR1 antibody
    • SWR1, S. cerevisiae, homologof antibody
    see all

References for Anti-SRCAP antibody (ab99408)

This product has been referenced in:
  • Seo J  et al. Genome-wide reorganization of histone H2AX toward particular fragile sites on cell activation. Nucleic Acids Res N/A:N/A (2013). WB ; Human . Read more (PubMed: 24163101) »

See 1 Publication for this product

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Ab99408 is produced outside of the US, so unfortunately we are not able to ship this product into Canada.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"