Publishing research using ab30682? Please let us know so that we can cite the reference in this datasheet.
ab30682 has been referenced in 49 publications.
Mohamed A et al.Aß inhibits SREBP-2 activation through Akt inhibition.J Lipid Res 59:1-13 (2018).
WB
.
PubMed: 29122977
Feng S et al.NS5ABP37 inhibits liver cancer by impeding lipogenesis and cholesterogenesis.Cancer Sci 108:12-22 (2017).
WB
;
Human
.
PubMed: 27862769
Vienken H et al.Characterization of cholesterol homeostasis in sphingosine-1-phosphate lyase-deficient fibroblasts reveals a Niemann-Pick disease type C-like phenotype with enhanced lysosomal Ca(2+) storage.Sci Rep 7:43575 (2017).
WB
.
PubMed: 28262793
Casagrande V et al.Hepatocyte specific TIMP3 expression prevents diet dependent fatty liver disease and hepatocellular carcinoma.Sci Rep 7:6747 (2017).
WB
;
Mouse
.
PubMed: 28751722
Giampietro C et al.Cholesterol impairment contributes to neuroserpin aggregation.Sci Rep 7:43669 (2017).
WB
.
PubMed: 28255164
Wang WA et al.Loss of Calreticulin Uncovers a Critical Role for Calcium in Regulating Cellular Lipid Homeostasis.Sci Rep 7:5941 (2017).
PubMed: 28725049
Rideout TC et al.Complementary Cholesterol-Lowering Response of a Phytosterol/a-Lipoic Acid Combination in Obese Zucker Rats.J Diet Suppl 13:283-99 (2016).
PubMed: 25664679
Mustafa M et al.SREBP inhibition ameliorates renal injury after unilateral ureteral obstruction.Am J Physiol Renal Physiol 311:F614-25 (2016).
PubMed: 27385736
Tang H et al.Irisin Inhibits Hepatic Cholesterol Synthesis via AMPK-SREBP2 Signaling.EBioMedicine 6:139-148 (2016).
PubMed: 27211556
Morioka S et al.TAK1 regulates hepatic lipid homeostasis through SREBP.Oncogene 35:3829-38 (2016).
PubMed: 26973245
Li X et al.SREBP-2 promotes stem cell-like properties and metastasis by transcriptional activation of c-Myc in prostate cancer.Oncotarget 7:12869-84 (2016).
WB
.
PubMed: 26883200
Mishra S et al.Accumulation of cholesterol and increased demand for zinc in serum-deprived RPE cells.Mol Vis 22:1387-1404 (2016).
WB
.
PubMed: 28003730
Xu D et al.PAQR3 modulates cholesterol homeostasis by anchoring Scap/SREBP complex to the Golgi apparatus.Nat Commun 6:8100 (2015).
WB
;
Human
.
PubMed: 26311497
Kang J et al.Simultaneous deletion of the methylcytosine oxidases Tet1 and Tet3 increases transcriptome variability in early embryogenesis.Proc Natl Acad Sci U S A 112:E4236-45 (2015).
PubMed: 26199412
Zheng W et al.Pathways of cholesterol homeostasis in mouse retina responsive to dietary and pharmacologic treatments.J Lipid Res 56:81-97 (2015).
PubMed: 25293590
Wong TY et al.The Flavone Luteolin Suppresses SREBP-2 Expression and Post-Translational Activation in Hepatic Cells.PLoS One 10:e0135637 (2015).
WB
.
PubMed: 26302339
Li M et al.MicroRNA-185-5p mediates regulation of SREBP2 expression by hepatitis C virus core protein.World J Gastroenterol 21:4517-25 (2015).
PubMed: 25914460
Gabitova L et al.Endogenous Sterol Metabolites Regulate Growth of EGFR/KRAS-Dependent Tumors via LXR.Cell Rep 12:1927-38 (2015).
PubMed: 26344763
Mattos KA et al.Mycobacterium leprae intracellular survival relies on cholesterol accumulation in infected macrophages: a potential target for new drugs for leprosy treatment.Cell Microbiol 16:797-815 (2014).
PubMed: 24552180
Nikolaenko L et al.Testosterone replacement ameliorates nonalcoholic fatty liver disease in castrated male rats.Endocrinology 155:417-28 (2014).
PubMed: 24280056
Ma K et al.Overactivation of intestinal SREBP2 in mice increases serum cholesterol.PLoS One 9:e84221 (2014).
WB, IHC-Fr
;
Mouse
.
PubMed: 24465397
Yang M et al.Identification of miR-185 as a regulator of de novo cholesterol biosynthesis and low density lipoprotein uptake.J Lipid Res 55:226-38 (2014).
PubMed: 24296663
Carrier B et al.Alpha-lipoic acid reduces LDL-particle number and PCSK9 concentrations in high-fat fed obese Zucker rats.PLoS One 9:e90863 (2014).
WB
;
Rat
.
PubMed: 24595397
Rauer C et al.Sterol regulatory element-binding proteins are regulators of the rat thyroid peroxidase gene in thyroid cells.PLoS One 9:e91265 (2014).
WB
;
Human
.
PubMed: 24625548
Nakakuki M et al.A novel processing system of sterol regulatory element-binding protein-1c regulated by polyunsaturated fatty acid.J Biochem 155:301-13 (2014).
PubMed: 24729033
Rice LM et al.Protein Phosphatase 2A (PP2A) Regulates Low Density Lipoprotein Uptake through Regulating Sterol Response Element-binding Protein-2 (SREBP-2) DNA Binding.J Biol Chem 289:17268-17279 (2014).
WB
.
PubMed: 24770487
Poirier S et al.The epigenetic drug 5-azacytidine interferes with cholesterol and lipid metabolism.J Biol Chem 289:18736-51 (2014).
WB
;
Mouse, Human
.
PubMed: 24855646
Barbero-Camps E et al.Endoplasmic reticulum stress mediates amyloid ß neurotoxicity via mitochondrial cholesterol trafficking.Am J Pathol 184:2066-81 (2014).
Mouse
.
PubMed: 24815354
Zinkhan EK et al.Combination of intrauterine growth restriction and a high-fat diet impairs cholesterol elimination in rats.Pediatr Res N/A:N/A (2014).
Rat
.
PubMed: 25119340
Valenza M et al.Disruption of astrocyte-neuron cholesterol cross talk affects neuronal function in Huntington's disease.Cell Death Differ N/A:N/A (2014).
PubMed: 25301063
Chew WS & Ong WY Regulation of Calcium-Independent Phospholipase A2 Expression by Adrenoceptors and Sterol Regulatory Element Binding Protein-Potential Crosstalk Between Sterol and Glycerophospholipid Mediators.Mol Neurobiol N/A:N/A (2014).
PubMed: 25482049
Penque BA et al.Hexosamine biosynthesis impairs insulin action via a cholesterolgenic response.Mol Endocrinol 27:536-47 (2013).
PubMed: 23315940
Tao R et al.Hepatic SREBP-2 and cholesterol biosynthesis are regulated by FoxO3 and Sirt6.J Lipid Res 54:2745-53 (2013).
Mouse
.
PubMed: 23881913
Boschetti E et al.Influence of genotype on the modulation of gene and protein expression by n-3 LC-PUFA in rats.Genes Nutr 8:589-600 (2013).
WB
;
Rat
.
PubMed: 23744008
Yu Y et al.PKR-like endoplasmic reticulum kinase is necessary for lipogenic activation during HCMV infection.PLoS Pathog 9:e1003266 (2013).
WB
.
PubMed: 23592989
Wen S et al.Treadmill Exercise Training Modulates Hepatic Cholesterol Metabolism and Circulating PCSK9 Concentration in High-Fat-Fed Mice.J Lipids 2013:908048 (2013).
WB
.
PubMed: 23862065
Wu J et al.Kisspeptin-10 enhanced egg production in quails associated with the increase of triglyceride synthesis in liver.Asian-Australas J Anim Sci 26:1080-8 (2013).
WB
.
PubMed: 25049888
Daimiel LA et al.Promoter analysis of the DHCR24 (3ß-hydroxysterol ?(24)-reductase) gene: characterization of SREBP (sterol-regulatory-element-binding protein)-mediated activation.Biosci Rep 33:57-69 (2012).
PubMed: 23050906
Hu Y et al.In ovo leptin administration affects hepatic lipid metabolism and microRNA expression in newly hatched broiler chickens.J Anim Sci Biotechnol 3:16 (2012).
WB
.
PubMed: 22958551
Ying Z et al.Modified methylenedioxyphenol analogs lower LDL cholesterol through induction of LDL receptor expression.J Lipid Res 53:879-87 (2012).
PubMed: 22355094
Johnson KJ et al.Species-specific dibutyl phthalate fetal testis endocrine disruption correlates with inhibition of SREBP2-dependent gene expression pathways.Toxicol Sci 120:460-74 (2011).
Rat
.
PubMed: 21266533
Spencer CM et al.Human cytomegalovirus induces the activity and expression of acetyl-coenzyme A carboxylase, a fatty acid biosynthetic enzyme whose inhibition attenuates viral replication.J Virol 85:5814-24 (2011).
PubMed: 21471234
Peterson TR et al.mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway.Cell 146:408-20 (2011).
PubMed: 21816276
Luthi-Carter R et al.SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis.Proc Natl Acad Sci U S A 107:7927-32 (2010).
ICC/IF
;
Drosophila melanogaster
.
PubMed: 20378838
López-Soldado I et al.Suppression of VLDL secretion by cultured hepatocytes incubated with chylomicron remnants enriched in n-3 polyunsaturated fatty acids is regulated by hepatic nuclear factor-4alpha.Biochim Biophys Acta 1791:1181-9 (2009).
WB
;
Rat
.
PubMed: 19699314
König B et al.Effects of fish oil and conjugated linoleic acids on expression of target genes of PPAR alpha and sterol regulatory element-binding proteins in the liver of laying hens.Br J Nutr 100:355-63 (2008).
WB
;
Chicken
.
PubMed: 18205990
Tamboli IY et al.Loss of gamma-secretase function impairs endocytosis of lipoprotein particles and membrane cholesterol homeostasis.J Neurosci 28:12097-106 (2008).
WB
;
Mouse
.
PubMed: 19005074
Bell RD et al.SRF and myocardin regulate LRP-mediated amyloid-beta clearance in brain vascular cells.Nat Cell Biol : (2008).
IHC-Fr, ICC/IF, WB
;
Human
.
PubMed: 19098903
Koch A et al.Thermally oxidized oil increases the expression of insulin-induced genes and inhibits activation of sterol regulatory element-binding protein-2 in rat liver.J Nutr 137:2018-23 (2007).
PubMed: 17709436
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Get resources and offers direct to your inboxSign up