Overview

  • Product nameAnti-SRP72 antibody
    See all SRP72 primary antibodies
  • Description
    Rabbit polyclonal to SRP72
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Chicken, Cow, Dog
  • Immunogen

    Synthetic peptide corresponding to a region within internal sequence amino acids 540-589 (DSQPKEQGQG DLKKKKKKKK GKLPKNYDPK VTPDPERWLP MRERSYYRGR) of Human SRP72 (NP_008878).

  • Positive control
    • PANC-1 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab90302 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 75 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionSignal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. Binds the 7S RNA only in presence of SRP68. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function.
  • Involvement in diseaseBone marrow failure, familial
  • Sequence similaritiesBelongs to the SRP72 family.
    Contains 5 TPR repeats.
  • DomainThe C-terminus is essential for the interaction with the SRP68/7S RNA complex.
  • Cellular localizationCytoplasm. Endoplasmic reticulum.
  • Information by UniProt
  • Database links
  • Alternative names
    • BMFF antibody
    • BMFS1 antibody
    • Epididymis luminal protein 103 antibody
    • HEL103 antibody
    • Signal recognition particle 72 kDa protein antibody
    • Signal recognition particle 72kDa antibody
    • Signal recognition particle subunit SRP72 antibody
    • SRP72 antibody
    • SRP72_HUMAN antibody
    see all

Anti-SRP72 antibody images

  • Anti-SRP72 antibody (ab90302) at 1 µg/ml (in 5% skim milk / PBS buffer) + PANC-1 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 75 kDa

References for Anti-SRP72 antibody (ab90302)

ab90302 has not yet been referenced specifically in any publications.

Product Wall

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