Anti-SRP72 antibody - C-terminal (ab195308)

Overview

  • Product name
    Anti-SRP72 antibody - C-terminal
    See all SRP72 primary antibodies
  • Description
    Rabbit polyclonal to SRP72 - C-terminal
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: IP
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Sheep, Rabbit, Horse, Cow, Dog, Chimpanzee, Rhesus monkey, Gorilla, Opossum, Common marmoset, Orangutan, Elephant
  • Immunogen

    Synthetic peptide within Human SRP72 aa 621-671 (C terminal). The exact sequence is proprietary.
    Sequence:

    SSPPTSPRPGSAATVSASTSNIIPPRHQKPAGAPATKKKQQQKKKKGGKG GW


    Database link: O76094

  • Positive control
    • HeLa, 293T and mouse NIH3T3 cell lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab195308 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000 - 1/10000. Predicted molecular weight: 75 kDa.
  • Application notes
    Is unsuitable for IP.
  • Target

    • Function
      Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. Binds the 7S RNA only in presence of SRP68. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function.
    • Involvement in disease
      Bone marrow failure, familial
    • Sequence similarities
      Belongs to the SRP72 family.
      Contains 5 TPR repeats.
    • Domain
      The C-terminus is essential for the interaction with the SRP68/7S RNA complex.
    • Cellular localization
      Cytoplasm. Endoplasmic reticulum.
    • Information by UniProt
    • Database links
    • Alternative names
      • BMFF antibody
      • BMFS1 antibody
      • Epididymis luminal protein 103 antibody
      • HEL103 antibody
      • Signal recognition particle 72 kDa protein antibody
      • Signal recognition particle 72kDa antibody
      • Signal recognition particle subunit SRP72 antibody
      • SRP72 antibody
      • SRP72_HUMAN antibody
      see all

    Images

    • All lanes : Anti-SRP72 antibody - C-terminal (ab195308) at 0.1 µg/ml

      Lane 1 : HeLa cell lysate
      Lane 2 : 293T cell lysate
      Lane 3 : Jurkat cell lysate
      Lane 4 : Mouse TCMK-1 cell lysate
      Lane 5 : Mouse NIH3T3 cell lysate

      Lysates/proteins at 50 µg per lane.

      Developed using the ECL technique

      Predicted band size : 75 kDa


      Exposure time : 30 seconds

    References

    ab195308 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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