Overview

  • Product nameAnti-SRPK1 antibody
    See all SRPK1 primary antibodies
  • Description
    Mouse monoclonal to SRPK1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: NETLRHKEDL HNANDCDVQN LNQESSFLSS QNGDSSTSQE TDSCTPITSE VSDTMVCQSS STVGQSFSEQ HISQLQESIR AEIPCEDEQE QEHNGPLDNK , corresponding to amino acids 371-470 of Human SRPK1

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • PurityProtein G purified
  • ClonalityMonoclonal
  • IsotypeIgG2a
  • Light chain typekappa
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab58003 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionPlays a central role in the regulatory network for splicing, controlling the intranuclear distribution of splicing factors in interphase cells and the reorganization of nuclear speckles during mitosis. Hyperphosphorylates RS domain-containing proteins such as SFRS1, SFRS2 and ZRSR2 on serine residues during metaphase but at lower levels during interphase. Locks onto SFRS1 to form a stable complex and processively phosphorylates the RS domain. Appears to mediate HBV core protein phosphorylation which is a prerequisite for pregenomic RNA encapsidation into viral capsids.
    • Tissue specificityIsoform 2 is predominantly expressed in the testis but is also present at lower levels in heart, ovary, small intestine, liver, kidney, pancreas and skeletal muscle. Isoform 1 is only seen in the testis, at lower levels than isoform 2.
    • Sequence similaritiesBelongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.
      Contains 1 protein kinase domain.
    • Cellular localizationCytoplasm. Nucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • Serine/arginine rich protein specific kinase 1 antibody
      • Serine/arginine rich splicing factor kinase 1 antibody
      • Serine/arginine-rich protein-specific kinase 1 antibody
      • Serine/threonine protein kinase SRPK1 antibody
      • Serine/threonine-protein kinase SRPK1 antibody
      • SFRS protein kinase 1 antibody
      • SFRSK1 antibody
      • SR protein kinase 1 antibody
      • SR protein specific kinase 1 antibody
      • SR-protein-specific kinase 1 antibody
      • SRPK1 antibody
      • SRPK1_HUMAN antibody
      see all

    Anti-SRPK1 antibody images



    • Predicted band size : 92 kDa
      SRPK1 antibody (ab58003) at 1ug/lane + HeLa cell lysate at 25ug/lane.

    References for Anti-SRPK1 antibody (ab58003)

    ab58003 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab58003.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"