Overview

  • Product name
  • Description
    Sheep polyclonal to SRPR beta
  • Tested applications
    Suitable for: WB, IPmore details
  • Species reactivity
    Reacts with: Dog
  • Immunogen

    Synthetic peptide, corresponding to C terminal amino acids 246-265 of Dog SRPR beta.

  • Positive control
    • Canine microsomal protein.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    Preservative: 0.08% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • Purification notes
    Purified by ammonium sulfate precipitation This antibody is provided as a 0.2 µm sterile filtered solution.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab16146 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 5 µg/ml. Detects a band of approximately 30 kDa.
IP Use at an assay dependent dilution.

Target

  • Function
    Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system. Has GTPase activity. May mediate the membrane association of SRPR.
  • Sequence similarities
    Belongs to the SRP receptor beta subunit family.
  • Cellular localization
    Endoplasmic reticulum membrane.
  • Information by UniProt
  • Alternative names
    • APMCF1 antibody
    • Protein APMCF1 antibody
    • Signal recognition particle receptor B subunit antibody
    • Signal recognition particle receptor beta subunit antibody
    • Signal recognition particle receptor subunit beta antibody
    • SR-beta antibody
    • SRbeta antibody
    • SRPR beta antibody
    • Srprb antibody
    • SRPRB_HUMAN antibody
    see all

Anti-SRPR beta antibody images

  • ab16146 detecting SRPR beta from canine microsomal protein by western blot Lane 1: 3ng of canine microsomal protein Lane 2: 6ng of canine microsomal protein Lane 3: 12ng of canine microsoaml protein

References for Anti-SRPR beta antibody (ab16146)

This product has been referenced in:
  • Lakkaraju AK  et al. Efficient secretion of small proteins in mammalian cells relies on Sec62-dependent posttranslational translocation. Mol Biol Cell 23:2712-22 (2012). WB . Read more (PubMed: 22648169) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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