The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 1 - 5 µg/ml. Detects a band of approximately 30 kDa.
Use at an assay dependent dilution.
FunctionComponent of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system. Has GTPase activity. May mediate the membrane association of SRPR.
Sequence similaritiesBelongs to the SRP receptor beta subunit family.
Signal recognition particle receptor B subunit antibody
Signal recognition particle receptor beta subunit antibody
Signal recognition particle receptor subunit beta antibody
SRPR beta antibody
Anti-SRPR beta antibody images
Western blot - SRPR beta antibody (ab16146)
ab16146 detecting SRPR beta from canine microsomal protein by western blot
Lane 1: 3ng of canine microsomal protein
Lane 2: 6ng of canine microsomal protein
Lane 3: 12ng of canine microsoaml protein
References for Anti-SRPR beta antibody (ab16146)
This product has been referenced in:
Lakkaraju AK et al. Efficient secretion of small proteins in mammalian cells relies on Sec62-dependent posttranslational translocation. Mol Biol Cell23:2712-22 (2012).
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