• Product nameAnti-SS18 antibody
    See all SS18 primary antibodies
  • Description
    Rabbit polyclonal to SS18
  • Specificityab66013 detects endogenous levels of total SS18 protein.
  • Tested applicationsSuitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide derived from N terminus of human SS18.

  • Positive control
    • Extracts from HepG2 cells, COLO205 cells and Jurkat cells.



Our Abpromise guarantee covers the use of ab66013 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/5000.
WB 1/500 - 1/1000. Detects a band of approximately 44 kDa (predicted molecular weight: 42 kDa).


  • FunctionAppears to function synergistically with RBM14 as a transcriptional coactivator. Isoform 1 and isoform 2 function in nuclear receptor coactivation. Isoform 1 and isoform 2 function in general transcriptional coactivation.
  • Tissue specificityFairly ubiquitously expressed. Expressed in synovial sarcomas and in other human cell lines. The fusion genes SSXT-SSX1 and SSXT-SSX2 are expressed only in synovial sarcomas.
  • Involvement in diseaseNote=A chromosomal aberration involving SS18 may be a cause of synovial sarcoma. Translocation t(X;18)(p11.2;q11.2). The translocation is specifically found in more than 80% of synovial sarcoma. The fusion products SSXT-SSX1 or SSXT-SSX2 are probably responsible for transforming activity. Heterogeneity in the position of the breakpoint can occur (low frequency).
  • Sequence similaritiesBelongs to the SS18 family.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • MGC116875 antibody
    • Protein SSXT antibody
    • Protein SYT antibody
    • SS18 antibody
    • SSXT antibody
    • SSXT/SSX4v fusion antibody
    • SSXT_HUMAN antibody
    • Synovial sarcoma translocated to X chromosome antibody
    • Synovial sarcoma translocated to X chromosome protein antibody
    • Synovial sarcoma translocation chromosome 18 antibody
    • SYT antibody
    • SYT SSX1 antibody
    • SYT SSX2 antibody
    • SYT/SSX4v fusion protein antibody
    • SYTSSX1 antibody
    • SYTSSX2 antibody
    see all

Anti-SS18 antibody images

  • All lanes : Anti-SS18 antibody (ab66013) at 1/500 dilution

    Lane 1 : HepG2 cell extracts
    Lane 2 : COLO205 cell extracts
    Lane 3 : Jurkat cell extracts
    Lane 4 : Jurkat cell extracts with immunising peptide at 10 µg

    Lysates/proteins at 30 µg per lane.

    Predicted band size : 42 kDa
    Observed band size : 44 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 120 kDa,30 kDa,80 kDa. We are unsure as to the identity of these extra bands.

References for Anti-SS18 antibody (ab66013)

ab66013 has not yet been referenced specifically in any publications.

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