• Product nameAnti-SSB antibody
    See all SSB primary antibodies
  • Description
    Rabbit polyclonal to SSB
  • Tested applicationsSuitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
  • Immunogen

    A region within synthetic peptide: ISEDKTKIRR SPSKPLPEVT DEYKNDVKNR SVYIKGFPTD ATLDDIKEWL, corresponding to amino acids 82-131 of Human SSB

  • Positive control
    • Jurkat cell lysate and human liver and kidney tissue.



Our Abpromise guarantee covers the use of ab50573 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 4 - 8 µg/ml.
WB Use a concentration of 0.25 µg/ml. Predicted molecular weight: 45 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.


  • FunctionBinds to the 3' poly(U) terminii of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation.
  • Sequence similaritiesContains 1 HTH La-type RNA-binding domain.
    Contains 1 RRM (RNA recognition motif) domain.
  • Post-translational
    Phosphorylated. The phosphorylation sites are at the C-terminal part of the protein.
    The N-terminus is blocked.
  • Cellular localizationNucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Autoantigen La antibody
    • La antibody
    • La autoantigen antibody
    • La autoantigen homolog antibody
    • La protein antibody
    • La ribonucleoprotein antibody
    • La ribonucleoprotein domain family member 3 antibody
    • LA_HUMAN antibody
    • LARP3 antibody
    • Lupus La antigen antibody
    • Lupus La protein antibody
    • Lupus La protein homolog antibody
    • MGC118101 antibody
    • MGC93380 antibody
    • mRNA for autoantigen antibody
    • OTTMUSP00000014043 antibody
    • RP23 273G23.1 antibody
    • Sjoegren syndrome type B antigen antibody
    • Sjogren syndrome antigen B (autoantigen La) antibody
    • Sjogren syndrome antigen B antibody
    • SS B antibody
    • SS-B antibody
    • SS-B/La protein antibody
    • SSB antibody
    see all

Anti-SSB antibody images

  • Anti-SSB antibody (ab50573) at 0.25 µg/ml + Jurkat cell lysate at 10 µg

    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 45 kDa
    Observed band size : 50 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 75 kDa. We are unsure as to the identity of these extra bands.
  • ab50573 at 4ug/ml dilution staining hepatocytes in human liver by Immunohistochemistry, Paraffin embedded tissue.
  • ab50573 at 4ug/ml dilution staining epithelial cells of renal tubule in human kidney by Immunohistochemistry, Paraffin embedded tissue.
  • ab50573 at 5µg/ml staining SSB in Human liver tissue by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).
  • ab50573 at 5µg/ml staining SSB in Human prostate tissue by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).
  • All lanes : Anti-SSB antibody (ab50573) at 2 µg

    Lane 1 : Jurkat cell lysate
    Lane 2 : Jurkat cell lysate with blocking peptide at 2 µg/ml

    Lysates/proteins at 25 µg per lane.

    Predicted band size : 45 kDa

References for Anti-SSB antibody (ab50573)

ab50573 has not yet been referenced specifically in any publications.

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