Overview

  • Product nameAnti-SSH2 antibody
  • Description
    Rabbit polyclonal to SSH2
  • Tested applicationsSuitable for: WB, IPmore details
  • Species reactivity
    Reacts with: Recombinant Fragment
    Predicted to work with: Human
  • Immunogen

    Recombinant full length protein corresponding to Human SSH2 aa 1-178.
    Sequence:

    MIPYFSANAVISQNAINQLISESFLTVKGAALFLPRGNGSSTPRISHRRN KHAGDLQQHLQAMFILLRPEDNIRLAVRLESTYQNRTRYMVVVSTNGRQD TEESIVLGMDFSSNDSSTCTMGLVLPLWSDTLIHLDGDGGFSVSTDNRVH IFKPVSVQAMWVDRDSRNKHCDVLLVEE


    Database link: AAH11636.2

  • Positive control
    • SSH2 transfected 293T cell lysate, recombinant SSH2 protein

Properties

Applications

Our Abpromise guarantee covers the use of ab118079 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 158 kDa.

Different isoforms of SSH2 may produce bands at a lower molecular weight to the predicted.

IP Use at an assay dependent concentration.

Target

  • FunctionProtein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein.
  • Sequence similaritiesBelongs to the protein-tyrosine phosphatase family.
    Contains 1 tyrosine-protein phosphatase domain.
  • Cellular localizationCytoplasm > cytoskeleton.
  • Information by UniProt
  • Database links
  • Alternative names
    • hSSH 2L antibody
    • hSSH-2L antibody
    • KIAA1725 antibody
    • MGC78588 antibody
    • OTTHUMP00000163634 antibody
    • OTTHUMP00000163635 antibody
    • Protein phosphatase Slingshot homolog 2 antibody
    • Slingshot 2 antibody
    • Slingshot homolog 2 (Drosophila) antibody
    • Slingshot homolog 2 antibody
    • Slingshot2 antibody
    • SSH 2 antibody
    • SSH 2L antibody
    • SSH-2L antibody
    • SSH-like protein 2 antibody
    • SSH2 antibody
    • SSH2_HUMAN antibody
    • SSH2L antibody
    see all

Anti-SSH2 antibody images

  • All lanes : Anti-SSH2 antibody (ab118079) at 1/1000 dilution

    Lane 1 : SSH2 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 158 kDa
    Observed band size : 20 kDa (why is the actual band size different from the predicted?)

    Cells were transfected with the protein used as the immunogen (AAH11636.2)

  • Immunoprecipitation of SSH2 transfected lysate using ab118079.

     

    Cells were transfected with the protein used as the immunogen (AAH11636.2)

References for Anti-SSH2 antibody (ab118079)

ab118079 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"