Overview

  • Product nameAnti-SSX1 antibody
    See all SSX1 primary antibodies
  • Description
    Mouse polyclonal to SSX1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length human SSX1 protein

  • Positive control
    • SSX1 transfected 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab72622 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 22 kDa.

Target

  • FunctionCould act as a modulator of transcription.
  • Tissue specificityExpressed at high level in the testis. Expressed at low level in thyroid. Not detected in tonsil, colon, lung, spleen, prostate, kidney, striated and smooth muscles. Detected in rhabdomyosarcoma and fibrosarcoma cell lines. Not detected in mesenchymal and epithelial cell lines.
  • Involvement in diseaseNote=A chromosomal aberration involving SSX1 may be a cause of synovial sarcoma. Translocation t(X;18)(p11.2;q11.2). The translocation is specifically found in more than 80% of synovial sarcoma. The fusion products SSXT-SSX1 or SSXT-SSX2 are probably responsible for transforming activity. Heterogeneity in the position of the breakpoint can occur (low frequency).
  • Sequence similaritiesBelongs to the SSX family.
    Contains 1 KRAB-related domain.
  • Information by UniProt
  • Database links
  • Alternative names
    • Cancer/testis antigen 5.1 antibody
    • Cancer/testis antigen family 5 member 1 antibody
    • CT5.1 antibody
    • MGC150425 antibody
    • MGC5162 antibody
    • Protein SSX1 antibody
    • sarcoma, synovial, X chromosome related 1 antibody
    • SSRC antibody
    • SSX1 antibody
    • SSX1_HUMAN antibody
    • Synovial sarcoma antibody
    • Synovial sarcoma, X breakpoint 1 antibody
    • X breakpoint 1 antibody
    see all

Anti-SSX1 antibody images

  • All lanes : Anti-SSX1 antibody (ab72622) at 1/500 dilution

    Lane 1 : SSX1 transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat anti-mouse IgG at 1/2500 dilution

    Predicted band size : 22 kDa
    Observed band size : 25 kDa (why is the actual band size different from the predicted?)

References for Anti-SSX1 antibody (ab72622)

ab72622 has not yet been referenced specifically in any publications.

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