Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab172209 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 25 kDa.

Target

  • Function
    Could act as a modulator of transcription.
  • Tissue specificity
    Expressed at high level in the testis. Expressed at low level in thyroid. Not detected in tonsil, colon, lung, spleen, prostate, kidney, striated and smooth muscles. Detected in rhabdomyosarcoma and fibrosarcoma cell lines. Not detected in mesenchymal and epithelial cell lines.
  • Involvement in disease
    Note=A chromosomal aberration involving SSX2 may be a cause of synovial sarcoma. Translocation t(X;18)(p11.2;q11.2). The translocation is specifically found in more than 80% of synovial sarcoma. The fusion products SSXT-SSX1 or SSXT-SSX2 are probably responsible for transforming activity. Heterogeneity in the position of the breakpoint can occur (low frequency).
  • Sequence similarities
    Belongs to the SSX family.
    Contains 1 KRAB-related domain.
  • Cellular localization
    Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Cancer/testis antigen 5.2 antibody
    • Cancer/testis antigen family 5, member 2a antibody
    • Cancer/testis antigen family 5, member 2b antibody
    • CT5.2 antibody
    • CT5.2A antibody
    • CT5.2b antibody
    • HD21 antibody
    • hom mel 40 antibody
    • HOM-MEL-40 antibody
    • MGC119055 antibody
    • MGC15364 antibody
    • MGC3884 antibody
    • Protein SSX2 antibody
    • RP11-552J9.2 antibody
    • sarcoma, synovial, X-chromosome related 2 antibody
    • SSx antibody
    • SSX2 antibody
    • SSX2-SYT fusion gene, included antibody
    • SSX2_HUMAN antibody
    • SSX2B antibody
    • Synovial sarcoma antibody
    • synovial sarcoma X breakpoint 2 antibody
    • Synovial sarcoma, X breakpoint 2B antibody
    • Tumor antigen HOM-MEL-40 antibody
    • X breakpoint 2 antibody
    see all

Images

  • All lanes : Anti-SSX2 antibody (ab172209) at 1 µg/ml

    Lane 1 : SSX2 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 15 µl per lane.

    Secondary
    All lanes : Goat Anti-Rabbit IgG at 1/7500 dilution

    Predicted band size: 25 kDa

References

ab172209 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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