Overview

  • Product name
  • Description
    Rabbit polyclonal to ST14
  • Tested applications
    Suitable for: WB, ELISA, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    synthesized peptide derived from N-terminal of human ST14.

Properties

Applications

Our Abpromise guarantee covers the use of ab73568 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000.
ELISA 1/10000.
ICC/IF 1/500 - 1/1000.

Target

  • Function
    Degrades extracellular matrix. Proposed to play a role in breast cancer invasion and metastasis. Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site.
  • Involvement in disease
    Defects in ST14 are a cause of ichthyosis autosomal recessive with hypotrichosis (ARIH) [MIM:610765]. ARIH is a skin disorder characterized by congenital ichthyosis associated with the presence of less than the normal amount of hair.
  • Sequence similarities
    Belongs to the peptidase S1 family.
    Contains 2 CUB domains.
    Contains 4 LDL-receptor class A domains.
    Contains 1 peptidase S1 domain.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Epithin antibody
    • HAI antibody
    • Matriptase antibody
    • Membrane type serine protease 1 antibody
    • Membrane type serine protease antibody
    • Membrane-type serine protease 1 antibody
    • MT SP1 antibody
    • MT-SP1 antibody
    • MTSP 1 antibody
    • MTSP1 antibody
    • Prostamin antibody
    • PRSS 14 antibody
    • PRSS14 antibody
    • Serine protease 14 antibody
    • Serine protease TADG 15 antibody
    • Serine protease TADG-15 antibody
    • Serine protease TADG15 antibody
    • SNC 19 antibody
    • SNC19 antibody
    • ST 14 antibody
    • ST14 antibody
    • ST14_HUMAN antibody
    • Suppression of tumorigenicity 14 (colon carcinoma matriptase epithin) antibody
    • Suppression of tumorigenicity 14 (colon carcinoma) antibody
    • Suppression of tumorigenicity 14 antibody
    • Suppressor of tumorigenicity 14 protein antibody
    • Suppressor of tumorigenicity protein 14 antibody
    • TADG 15 antibody
    • TADG15 antibody
    • TMPRSS14 antibody
    • Tumor associated differentially expressed gene 15 protein antibody
    • Tumor-associated differentially-expressed gene 15 protein antibody
    see all

References

ab73568 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Application
Immunocytochemistry/ Immunofluorescence
Sample
Rat Cell (Rat hepatocytes)
Permeabilization
Yes - 0.2% Triton X-100 in PBS
Specification
Rat hepatocytes
Blocking step
Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 1% · Temperature: 22°C
Fixative
Formaldehyde
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Submitted Nov 06 2017

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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