Overview

  • Product nameAnti-ST2 antibody
    See all ST2 primary antibodies
  • Description
    Rabbit polyclonal to ST2
  • Specificityab72778 is specific to Isoform C of ST2
  • Tested applicationsSuitable for: Flow Cyt, WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide corresponding to a region between residues 200-250 of human ST2 protein

  • Positive control
    • Daudi and NIH3T3 cell lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab72778 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use at an assay dependent concentration. PubMed: 24388011ab171870-Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.
WB Use a concentration of 3 - 5 µg/ml. Detects a band of approximately 29 kDa (predicted molecular weight: 29 kDa).

Target

  • FunctionReceptor for interleukin-33 (IL-33), its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Possibly involved in helper T-cell function.
  • Tissue specificityHighly expressed in kidney, lung, placenta, stomach, skeletal muscle, colon and small intestine. Isoform A is prevalently expressed in the lung, testis, placenta, stomach and colon. Isoform B is more abundant in the brain, kidney and the liver. Isoform C is not detected in brain, heart, liver, kidney and skeletal muscle.
  • Sequence similaritiesBelongs to the interleukin-1 receptor family.
    Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 1 TIR domain.
  • Cellular localizationSecreted and Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • DER-4 antibody
    • DER4 antibody
    • FIT 1 antibody
    • Growth stimulation expressed antibody
    • homolog of mouse growth stimulation-expressed antibody
    • Il1rl1 antibody
    • IL33R antibody
    • ILRL1_HUMAN antibody
    • Interleukin 1 receptor like 1 antibody
    • interleukin 1 receptor related protein antibody
    • Interleukin-1 receptor-like 1 antibody
    • Protein ST2 antibody
    • ST2 antibody
    • ST2L antibody
    • ST2V antibody
    • T1 antibody
    • T1 protein antibody
    see all

Anti-ST2 antibody images

  • Lanes 1 - 2 : Anti-ST2 antibody (ab72778) at 5 µg/ml
    Lane 3 : Anti-ST2 antibody (ab72778) at 3 µg/ml

    Lane 1 : Daudi cell lysate
    Lane 2 : Daudi cell lysate with immunizing peptide
    Lane 3 : NIH3T3 cell lysate


    Predicted band size : 29 kDa
    Observed band size : 29 kDa

References for Anti-ST2 antibody (ab72778)

This product has been referenced in:
  • Xue L  et al. Prostaglandin D2 activates group 2 innate lymphoid cells through chemoattractant receptor-homologous molecule expressed on TH2 cells. J Allergy Clin Immunol 133:1184-94 (2014). Flow Cyt ; Human . Read more (PubMed: 24388011) »

See 1 Publication for this product

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