Overview

  • Product name
  • Description
    Rabbit polyclonal to ST3GAL5
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, between amino acids 396-426 from the C-terminal region of Human ST3GAL5 (NP_003887.3, NP_001035902.1).

  • Positive control
    • Jurkat cell line lysate, Human skeletal muscle

Properties

Applications

Our Abpromise guarantee covers the use of ab107534 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 48 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Catalyzes the formation of ganglioside GM3 (alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1, 4-beta-D-glucosylceramide).
  • Tissue specificity
    Ubiquitous. High expression in brain, skeletal muscle, placenta, and testis.
  • Involvement in disease
    Defects in ST3GAL5 are the cause of Amish infantile epilepsy syndrome (AIES) [MIM:609056]. AIES is an autosomal recessive, infantile-onset symptomatic epilepsy associated with developmental stagnation and blindness.
  • Sequence similarities
    Belongs to the glycosyltransferase 29 family.
  • Post-translational
    modifications
    N-glycosylated.
  • Cellular localization
    Golgi apparatus membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 3-sialyltransferase antibody
    • CMP-NeuAc:lactosylceramide alpha-2 antibody
    • CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase antibody
    • EC 2.4.99.9 antibody
    • Ganglioside GM3 synthase antibody
    • Lactosylceramide alpha-2,3-sialyltransferase antibody
    • Sialyltransferase 9 antibody
    • SIAT9 antibody
    • SIAT9_HUMAN antibody
    • SIATGM3S antibody
    • ST3 beta-galactoside alpha-2,3-sialyltransferase 5 antibody
    • ST3GAL antibody
    • ST3Gal V antibody
    • ST3GAL5 antibody
    • ST3GalV antibody
    see all

Anti-ST3GAL5 antibody images

  • Anti-ST3GAL5 antibody (ab107534) at 1/100 dilution + Jurkat cell line lysate at 35 µg

    Predicted band size : 48 kDa
  • Immunohistochemistry analysis in formalin fixed and paraffin embedded Human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. ab107534 at a dilution of 1/50.

References for Anti-ST3GAL5 antibody (ab107534)

ab107534 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab107534.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up