Overview

  • Product name
    Anti-ST3GAL6 antibody
  • Description
    Rabbit polyclonal to ST3GAL6
  • Tested applications
    Suitable for: WB, ICCmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide: 16 amino acid peptide from near the carboxy terminus of human ST3GAL6.

  • Positive control
    • HeLa cell lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at 4°C (stable for up to 12 months).
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab106527 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 38 kDa.
ICC Use a concentration of 5 µg/ml.

Target

  • Function
    Involved in the synthesis of sialyl-paragloboside, a precursor of sialyl-Lewis X determinant. Has a alpha-2,3-sialyltransferase activity toward Gal-beta1,4-GlcNAc structure on glycoproteins and glycolipids. Has a restricted substrate specificity, it utilizes Gal-beta1,4-GlcNAc on glycoproteins, and neolactotetraosylceramide and neolactohexaosylceramide, but not lactotetraosylceramide, lactosylceramide or asialo-GM1.
  • Tissue specificity
    Ubiquitous.
  • Sequence similarities
    Belongs to the glycosyltransferase 29 family.
  • Cellular localization
    Golgi apparatus membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • SIAT10 antibody
    • 3-sialyltransferase VI antibody
    • alpha-2,3-sialyltransferase VI antibody
    • alpha2,3-sialyltransferase antibody
    • CMP-NeuAc:beta-galactoside alpha-2 antibody
    • CMP-NeuAc:beta-galactoside alpha-2,3-sialyltransferase VI antibody
    • SIA10_HUMAN antibody
    • Sialyltransferase 10 antibody
    • ST3Gal VI antibody
    • ST3GAL6 antibody
    • ST3GalVI antibody
    • Type 2 lactosamine alpha-2,3-sialyltransferase antibody
    see all

Images

  • Lane 1 : Anti-ST3GAL6 antibody (ab106527) at 1 µg/ml
    Lane 2 : Anti-ST3GAL6 antibody (ab106527) at 2 µg/ml

    Lane 1 : HeLa cell lysate
    Lane 2 : HeLa cell lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 38 kDa
  • ab106527, at 5 µg/ml, staining ST3GAL6 by immunocytochemistry

References

This product has been referenced in:
  • Wu Y  et al. Induction of Siglec-1 by Endotoxin Tolerance Suppresses the Innate Immune Response by Promoting TGF-ß1 Production. J Biol Chem 291:12370-82 (2016). Read more (PubMed: 27129263) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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