Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab37806 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000. Predicted molecular weight: 41 kDa.

Target

  • Function
    Involved in the production of gangliosides GD3 and GT3 from GM3; gangliosides are a subfamily of complex glycosphinglolipds that contain one or more residues of sialic acid.
  • Tissue specificity
    Strongly expressed in melanoma cell lines, adult and fetal brain and to a lesser extent in adult and fetal lung.
  • Pathway
    Protein modification; protein glycosylation.
    Lipid metabolism; sphingolipid metabolism.
  • Sequence similarities
    Belongs to the glycosyltransferase 29 family.
  • Cellular localization
    Golgi apparatus membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 8-sialyltransferase 8A antibody
    • 8-sialyltransferase antibody
    • Alpha 2,8 sialyltransferase 8A antibody
    • Alpha N acetylneuraminide alpha 2,8 sialyltransferase antibody
    • Alpha-2 antibody
    • Alpha-N-acetylneuraminide alpha-2 antibody
    • Disialoganglioside (GD3) synthase antibody
    • Ganglioside GD3 synthase antibody
    • Ganglioside GT3 synthase antibody
    • Ganglioside specific alpha 2,8 polysialyltransferase antibody
    • GD3S antibody
    • SIA8A_HUMAN antibody
    • Sialyltransferase 8 (alpha N acetylneuraminate: alpha 2,8 sialytransferase, GD3 synthase) A antibody
    • Sialyltransferase 8A (alpha N acetylneuraminate: alpha 2,8 sialyltransferase, GD3 synthase) antibody
    • Sialyltransferase 8A antibody
    • Sialytransferase St8Sia I antibody
    • SIAT8 antibody
    • SIAT8-A antibody
    • SIAT8A antibody
    • ST8 alpha N acetyl neuraminide alpha 2,8 sialyltransferase 1 antibody
    • ST8 alpha N acetyl neuraminide alpha 28 sialyltransferase 1 antibody
    • ST8Sia I antibody
    • ST8SIA1 antibody
    • ST8SiaI antibody
    see all

Images

  • Anti-ST8SIA1 antibody (ab37806) at 1/2000 dilution + E. coli derived fusion protein at 2.5 µg

    Secondary
    HRP conjugated Goat anti IgY at 1/1000 dilution

    Predicted band size : 41 kDa
    Observed band size : 55 kDa (why is the actual band size different from the predicted?)

References

This product has been referenced in:
  • Sarkar TR  et al. GD3 synthase regulates epithelial-mesenchymal transition and metastasis in breast cancer. Oncogene 0:N/A (2014). Read more (PubMed: 25109336) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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