Overview

  • Product name
  • Description
    Goat polyclonal to stabilin1
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Cow, Dog, Pig
  • Immunogen

    Synthetic peptide:

    C-DFPDTQRILTVK

    , corresponding to C terminal amino acids 2559-2570 of Human stabilin1 (NP_055951.2).

Properties

Applications

Our Abpromise guarantee covers the use of ab101035 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 3 - 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Acts as a scavenger receptor for acetylated low density lipoprotein. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. When inhibited in endothelial tube formation assays, there is a marked decrease in cell-cell interactions, suggesting a role in angiogenesis. Involved in the delivery of newly synthesized CHID1/SI-CLP from the biosynthetic compartment to the endosomal/lysosomal system.
  • Tissue specificity
    High levels found in spleen, lymph node, liver and placenta. Also expressed in endothelial cells.
  • Sequence similarities
    Contains 16 EGF-like domains.
    Contains 7 FAS1 domains.
    Contains 2 laminin EGF-like domains.
    Contains 1 Link domain.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CLEVER 1 antibody
    • Common lymphatic endothelial and vascular endothelial receptor 1 antibody
    • EGF-like antibody
    • Fasciclin antibody
    • Fasciclin EGF like laminin type EGF like and link domain containing scavenger receptor 1 antibody
    • fasciclin egf-like antibody
    • FEEL 1 antibody
    • FEEL-1 antibody
    • FELE 1 antibody
    • FEX1 antibody
    • KIAA0246 antibody
    • laminin-type EGF-like and link domain-containing scavenger receptor 1 antibody
    • MS 1 antigen antibody
    • MS-1 antigen antibody
    • STAB 1 antibody
    • Stab1 antibody
    • STAB1_HUMAN antibody
    • Stabilin-1 antibody
    see all

Images

  • ab101035 (3.8µg/ml) staining of paraffin embedded Human Spleen following Steamed antigen retrieval with citrate buffer pH 6 and AP-staining shows endothelial staining.

References

ab101035 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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