Overview

  • Product name
  • Description
    Rabbit polyclonal to STAMBPL1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 1-50 (MDQPFTVNSL KKLAAMPDHT DVSLSPEERV RALSKLGCNI TISEDITPRR) of Human STAMBPL1 (NP_065850).

  • Positive control
    • Jurkat cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab99172 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 50 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains.
  • Tissue specificity
    Ubiquitously expressed.
  • Sequence similarities
    Belongs to the peptidase M67C family.
    Contains 1 MPN (JAB/Mov34) domain.
  • Domain
    The JAMM motif is essential for the protease activity.
  • Information by UniProt
  • Database links
  • Alternative names
    • ALMalpha antibody
    • AMSH FP antibody
    • AMSH LP antibody
    • AMSH-like protease antibody
    • AMSH-LP antibody
    • AMSHFP antibody
    • AMSHLP antibody
    • Associated molecule with the SH3 domain of STAM (AMSH) like protein antibody
    • FLJ31524 antibody
    • OTTHUMP00000020055 antibody
    • STALP_HUMAN antibody
    • STAM binding protein like 1 antibody
    • STAM-binding protein-like 1 antibody
    • STAMBPL1 antibody
    see all

Images

  • Anti-STAMBPL1 antibody (ab99172) at 1 µg/ml + Jurkat cell lysate at 10 µg

    Predicted band size : 50 kDa
    Gel concentration: 12%

References

This product has been referenced in:
  • Lavorgna A & Harhaj EW An RNA interference screen identifies the Deubiquitinase STAMBPL1 as a critical regulator of human T-cell leukemia virus type 1 tax nuclear export and NF-?B activation. J Virol 86:3357-69 (2012). WB . Read more (PubMed: 22258247) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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