Anti-STAP2 antibody (ab77191)

Overview

• Product name
  Anti-STAP2 antibody
  See all STAP2 primary antibodies
• Description
  Goat polyclonal to STAP2
• Specificity
  Expected to recognise both reported isoforms (NP_060190.2 and NP_001013863.1).
• Tested applications
  Suitable for: WB, IHC-Pmore details
• Species reactivity
  Reacts with: Human
  Predicted to work with: Mouse, Rat
• Immunogen

  Synthetic peptide:

  ELQKKLEKRRALEH

  from the C-terminal region of Human STAP2 (100% identity for both NP_060190.2 and NP_001013863.1)

  Run BLAST with Run BLAST with
• Positive control
  • Human heart lysate

Properties

• Form
  Liquid
• Storage instructions
  Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Storage buffer
  Preservative: 0.02% Sodium Azide
  Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
• Concentration information loading...
• Purity
  Immunogen affinity purified
• Purification notes
  Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• Clonality
  Polyclonal
• Isotype
  IgG
• Research areas
  • Immunology
  • Innate Immunity
  • Macrophage / Inflamm.

  • Signal Transduction
  • Adapters
  • Cytoplasmic

  • Signal Transduction
  • Signaling Pathway
  • Nuclear Signaling
  • STATs

  • Signal Transduction
  • Protein Phosphorylation
  • pTyr

  • Epigenetics and Nuclear Signaling
  • Nuclear Signaling Pathways
  • STATs

Associated products

• Compatible Secondaries
  • Donkey Anti-Goat IgG H&L (Alexa Fluor® 488) (ab150129)
  • Donkey Anti-Goat IgG H&L (HRP) (ab205723)

Applications

Target

• Function
  Substrate of protein kinase PTK6. May play a regulatory role in the acute-phase response in systemic inflammation and may modulate STAT3 activity.
• Tissue specificity
  Widely expressed.
• Sequence similarities
  Contains 1 PH domain.
  Contains 1 SH2 domain.
• Post-translational
  modifications
  Phosphorylated on tyrosine. Tyr-250 may be important for interaction with kinases. Tyr-22 and Tyr-322 appears to be phosphorylated by SRC.
• Cellular localization
  Cytoplasm.

• Target information above from: UniProt accession Q9UGK3 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• Database links
  • Entrez Gene: 55620 Human
  • Entrez Gene: 106766 Mouse
  • Entrez Gene: 363334 Rat
  • Omim: 607881 Human
  • SwissProt: Q9UGK3 Human
  • SwissProt: Q8R0L1 Mouse
  • Unigene: 194385 Human
  • Unigene: 204991 Mouse

  • Unigene: 19078 Rat

  see all
• Alternative names
  • BKS antibody
  • Breast tumor kinase substrate antibody
  • Brk kinase substrate antibody

  • BRK substrate antibody
  • Signal transducing adaptor protein 2 antibody
  • Signal-transducing adaptor protein 2 antibody
  • Ssignal transducing adaptor family member 2 antibody
  • STAP 2 antibody
  • STAP-2 antibody
  • STAP2 antibody
  • STAP2_HUMAN antibody

  see all

Protocols

• Western blot protocols
• Immunohistochemistry protocols