Anti-Staphylococcus aureus antibody [P4B5] (ab75246)

Overview

  • Product nameAnti-Staphylococcus aureus antibody [P4B5]
    See all Staphylococcus aureus primary antibodies
  • Description
    Mouse monoclonal [P4B5] to Staphylococcus aureus
  • SpecificitySpecific to an epitope on Protein A (a surface antigen on Staphlococcus aureus). Reacts to Staphlococcus aureus and purified Protein A.
  • Tested applicationsSuitable for: ELISAmore details
  • Species reactivity
    Reacts with
  • Immunogen

    Formal and fixed bacterial cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab75246 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution.

Target

  • RelevanceS.aureus binds IgG molecules by their Fc region. In serum, the bacteria will bind IgG molecules in the wrong orientation on their surface, which hinders opsonization and phagocytosis. Mutants of S. aureus lacking protein A are more efficiently phagocytosed in vitro, and mutants in infection models have diminished virulence. Due to its affinity for the Fc region of many mammalian immunoglobulins, protein A is considered a universal reagent in biochemistry and immunology.
  • Cellular localizationSecreted; cell wall.
  • Alternative names
    • IgG binding protein A antibody
    • Immunoglobulin G binding protein A antibody
    • SPA antibody

References for Anti-Staphylococcus aureus antibody [P4B5] (ab75246)

ab75246 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"