Anti-Staphylococcus aureus Enterotoxins B + C1 + C2 + D antibody [S5] (ab8311)

Overview

  • Product nameAnti-Staphylococcus aureus Enterotoxins B + C1 + C2 + D antibody [S5]
  • Description
    Mouse monoclonal [S5] to Staphylococcus aureus Enterotoxins B + C1 + C2 + D
  • SpecificityThis antibody detects enterotoxins A (2%), B (100%), C1 (7%), C2 (76%), and D (29%) of S. aureus
  • Tested applicationsSuitable for: ELISAmore details
  • Immunogen

    Purified enterotoxin A from FRI-722H strain of S. aureus

  • General notesAt 0,1 µM this antibody inhibits enterotoxins induced stimulation of T-lymphocytes in vitro


    Detection of enterotoxins from S. aureus

Properties

Applications

Our Abpromise guarantee covers the use of ab8311 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent concentration.

Target

  • RelevanceStaphylococcal enterotoxins represent a group of proteins, which are secreted by Staphylococcus aureus and cause the intoxication staphylococcal food poisoning syndrome. The illness characterised by high fever, hypotension, diarrhea, shock, and in some cases death. Their molecular masses range between 27 and 30 kDa. At present, seven enterotoxins are known, namely A, B, C1, C2, C3, D and E. Their amino acid sequences have been determined and it was shown that all are single chain polypeptides containing one disulfide bond formed by two half cystines located in the middle of the polypeptide chain, which form the so called cysteine loop. Enterotoxins are extremely potent activator of T cells, stimulating the production and secretion of various cytokines which mediate many of the toxic effects of these substances. Enterotoxins are Superantigens, inducing polyclonal T cell activation by binding to the TCR and to the alpha chain of the MHC II molecule simultaneously.
  • Alternative names
    • entB antibody
    • entC1 antibody
    • entC2 antibody
    • entD antibody
    • Enterotoxin type B antibody
    • Enterotoxin type C-1 antibody
    • Enterotoxin type C-2 antibody
    • Enterotoxin type D antibody
    • SEB antibody
    • SEC1 antibody
    • SEC2 antibody
    • SED antibody
    see all

References for Anti-Staphylococcus aureus Enterotoxins B + C1 + C2 + D antibody [S5] (ab8311)

ab8311 has not yet been referenced specifically in any publications.

Product Wall

You are quite right. The enterotoxin A was not as pure as originally thought, hence the strong cross reactions with other enterotoxins.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"