Overview

  • Product name
  • Description
    Rabbit polyclonal to StARD13
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence: NPVMLDAPLV SSSLPQPPRD VLNHPFHPKN EKPTRARAKS FLKRMETLRG KGAHGRHKGS GRTGGLVISG PMLQQEPESF KAMQCIQIPN GDLQNSPPPA CRKGLPC, corresponding to amino acids of Human StARD13.

  • Positive control
    • Human pancreas tissue; U251 MG and Human liver tissue lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab126489 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/250 - 1/500. Predicted molecular weight: 125 kDa.
IHC-P 1/200 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    GTPase-activating protein for RhoA, and perhaps for Cdc42. May be involved in regulation of cytoskeletal reorganization, cell proliferation and cell motility. Acts a tumor suppressor in hepatocellular carcinoma cells.
  • Tissue specificity
    Ubiquitously expressed. Underexpressed in hepatocellular carcinoma cells and some breast cancer cell lines.
  • Sequence similarities
    Contains 1 Rho-GAP domain.
    Contains 1 SAM (sterile alpha motif) domain.
    Contains 1 START domain.
  • Cellular localization
    Cytoplasm. Membrane. Mitochondrion membrane. Lipid droplet.
  • Information by UniProt
  • Database links
  • Alternative names
    • 46H23.2 antibody
    • ARHGAP37 antibody
    • Deleted in liver cancer 2 protein antibody
    • Deleted in liver cancer protein 2 antibody
    • DLC-2 antibody
    • DLC2 antibody
    • GT650 antibody
    • Rho GTPase activating protein on chromosome 13q12 antibody
    • Rho GTPase-activating protein antibody
    • STA13 antibody
    • STA13_HUMAN antibody
    • StAR related lipid transfer (START) domain containing 13 antibody
    • StAR-related lipid transfer protein 13 antibody
    • StARD13 antibody
    • START domain-containing protein 13 antibody
    see all

Images

  • ab126489 at 1/200 dilution staining StARD13 in paraffin-embedded Human pancreas tissue by Immunohistochemistry.
  • All lanes : Anti-StARD13 antibody (ab126489) at 1/250 dilution

    Lane 1 : RT4 cell lysate
    Lane 2 : U251 MG cell lysate
    Lane 3 : Human plasma lysate
    Lane 4 : Human liver tissue lysate
    Lane 5 : Human tonsil tissue lysate

    Developed using the ECL technique

    Predicted band size : 125 kDa

References

ab126489 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Thank you for providing details of the sample types.

Several isoforms (5) have been reported and it is very likely that the double band in certain lysates (HEK293T, HeLa, U251MG) represent some of the variants of StARD13. You and your custome...

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Thank you for your enquiry regarding ab126489 and for taking the time to provide some useful details of the experiments. I am very sorry to hear that you are having problems with this antibody.

Though you have kindly provided some details, it...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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