Anti-STAT3 (phospho Y705) antibody [EP2147Y] (ab76315)

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ab76315 has been referenced in 54 publications.

  • Enyu L  et al. The clinical significance and underlying correlation of pStat-3 and integrin avß6 expression in gallbladder cancer. Oncotarget 8:19467-19477 (2017). IHC-P ; Human . PubMed: 28061445
  • Wang D  et al. Maslinic acid suppresses the growth of human gastric cells by inducing apoptosis via inhibition of the interleukin-6 mediated Janus kinase/signal transducer and activator of transcription 3 signaling pathway. Oncol Lett 13:4875-4881 (2017). PubMed: 28599489
  • Li X  et al. Negative Regulation of Hepatic Inflammation by the Soluble Resistance-Related Calcium-Binding Protein via Signal Transducer and Activator of Transcription 3. Front Immunol 8:709 (2017). PubMed: 28706517
  • Wang Z  et al. NEAT1 modulates herpes simplex virus-1 replication by regulating viral gene transcription. Cell Mol Life Sci 74:1117-1131 (2017). WB . PubMed: 27783096
  • Yi L  et al. Inflammation-mediated SOD-2 upregulation contributes to epithelial-mesenchymal transition and migration of tumor cells in aflatoxin G1-induced lung adenocarcinoma. Sci Rep 7:7953 (2017). PubMed: 28801561
  • Yu PY  et al. Target specificity, in vivo pharmacokinetics, and efficacy of the putative STAT3 inhibitor LY5 in osteosarcoma, Ewing's sarcoma, and rhabdomyosarcoma. PLoS One 12:e0181885 (2017). PubMed: 28750090
  • Ball DP  et al. Signal transducer and activator of transcription 3 (STAT3) inhibitor, S3I-201, acts as a potent and non-selective alkylating agent. Oncotarget 7:20669-79 (2016). WB . PubMed: 26942696
  • Luo LN  et al. Osthole decreases renal ischemia-reperfusion injury by suppressing JAK2/STAT3 signaling activation. Exp Ther Med 12:2009-2014 (2016). WB ; Rat . PubMed: 27698686
  • Kling T  et al. Integrative Modeling Reveals Annexin A2-mediated Epigenetic Control of Mesenchymal Glioblastoma. EBioMedicine 12:72-85 (2016). WB . PubMed: 27667176
  • Liu Z  et al. Overexpression of variant PNPLA3 gene at I148M position causes malignant transformation of hepatocytes via IL-6-JAK2/STAT3 pathway in low dose free fatty acid exposure: a laboratory investigation in vitro and in vivo. Am J Transl Res 8:1319-38 (2016). PubMed: 27186262
  • Zhu L  et al. Crosstalk between bone marrow-derived myofibroblasts and gastric cancer cells regulates cancer stemness and promotes tumorigenesis. Oncogene 35:5388-5399 (2016). WB ; Human . PubMed: 27109105
  • Xue H  et al. A Novel Tumor-promoting Mechanism of IL6 and the Therapeutic Efficacy of Tocilizumab: Hypoxia-induced IL6 Is a Potent Autophagy Initiator in Glioblastoma via the p-STAT3-MIR155-3p-CREBRF Pathway. Autophagy N/A:0 (2016). WB ; Human . PubMed: 27163161
  • Liu F  et al. Silencing of Histone Deacetylase 9 Expression in Podocytes Attenuates Kidney Injury in Diabetic Nephropathy. Sci Rep 6:33676 (2016). WB . PubMed: 27633396
  • Zheng H  et al. TMED3 promotes hepatocellular carcinoma progression via IL-11/STAT3 signaling. Sci Rep 6:37070 (2016). WB ; Human . PubMed: 27901021
  • Peng HY  et al. MPT0B098, a Microtubule Inhibitor, Suppresses JAK2/STAT3 Signaling Pathway through Modulation of SOCS3 Stability in Oral Squamous Cell Carcinoma. PLoS One 11:e0158440 (2016). WB ; Human . PubMed: 27367272
  • Mishra V  et al. Sex-specific IL-6-associated signaling activation in ozone-induced lung inflammation. Biol Sex Differ 7:16 (2016). Mouse . PubMed: 26949510
  • Mao S  et al. miR-17-92 facilitates neuronal differentiation of transplanted neural stem/precursor cells under neuroinflammatory conditions. J Neuroinflammation 13:208 (2016). WB ; Mouse . PubMed: 27567678
  • Liu Y  et al. JAK2 inhibitor combined with DC-activated AFP-specific T-cells enhances antitumor function in a Fas/FasL signal-independent pathway. Onco Targets Ther 9:4425-33 (2016). WB ; Human . PubMed: 27499636
  • Toll A  et al. MiR-204 silencing in intraepithelial to invasive cutaneous squamous cell carcinoma progression. Mol Cancer 15:53 (2016). WB, IHC-Fr ; Human . PubMed: 27457246
  • Wang S  et al. Tocilizumab inhibits neuronal cell apoptosis and activates STAT3 in cerebral infarction rat model. Bosn J Basic Med Sci 16:145-50 (2016). WB ; Rat . PubMed: 26773188
  • Jing X  et al. Electroacupuncture Reduces Weight Gain Induced by Rosiglitazone through PPAR? and Leptin Receptor in CNS. Evid Based Complement Alternat Med 2016:8098561 (2016). WB ; Rat . PubMed: 26904147
  • Huang YH  et al. Postnatal High-Fat Diet Increases Liver Steatosis and Apoptosis Threatened by Prenatal Dexamethasone through the Oxidative Effect. Int J Mol Sci 17:369 (2016). WB ; Rat . PubMed: 26978357
  • Hiraoka T  et al. STAT3 accelerates uterine epithelial regeneration in a mouse model of decellularized uterine matrix transplantation. JCI Insight 1:N/A (2016). IHC-P ; Human . PubMed: 27358915
  • Su X  et al. Expression of FABP4, adipsin and adiponectin in Paneth cells is modulated by gut Lactobacillus. Sci Rep 5:18588 (2015). PubMed: 26687459
  • Cabello N  et al. Sex differences in the expression of lung inflammatory mediators in response to ozone. Am J Physiol Lung Cell Mol Physiol 309:L1150-63 (2015). WB ; Mouse . PubMed: 26342085
  • Svensson MN  et al. Murine germinal center B cells require functional Fms-like tyrosine kinase 3 signaling for IgG1 class-switch recombination. Proc Natl Acad Sci U S A 112:E6644-53 (2015). WB ; Mouse . PubMed: 26627255
  • Sperber H  et al. The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition. Nat Cell Biol 17:1523-35 (2015). WB ; Human . PubMed: 26571212
  • Zhu Z  et al. Phosphorylated AKT1 is associated with poor prognosis in esophageal squamous cell carcinoma. J Exp Clin Cancer Res 34:95 (2015). IHC-P ; Human . PubMed: 26338103
  • Ma L  et al. Trap Effect of Three-Dimensional Fibers Network for High Efficient Cancer-Cell Capture. Adv Healthc Mater 4:838-43 (2015). PubMed: 25645204
  • Huang S  et al. Attenuation of microRNA-16 derepresses the cyclins D1, D2 and E1 to provoke cardiomyocyte hypertrophy. J Cell Mol Med 19:608-19 (2015). WB . PubMed: 25583328
  • Andersson KM  et al. Down-regulation of survivin alleviates experimental arthritis. J Leukoc Biol 97:135-45 (2015). PubMed: 25381389
  • Schwartz C  et al. Melatonin receptor signaling contributes to neuroprotection upon arousal from torpor in thirteen-lined ground squirrels. Am J Physiol Regul Integr Comp Physiol 309:R1292-300 (2015). PubMed: 26354846
  • Zhao C  et al. microRNA-195 inhibits cell proliferation in bladder cancer via inhibition of cell division control protein 42 homolog/signal transducer and activator of transcription-3 signaling. Exp Ther Med 10:1103-1108 (2015). WB ; Human . PubMed: 26622447
  • Andersson KM  et al. Survivin co-ordinates formation of follicular T-cells acting in synergy with Bcl-6. Oncotarget 6:20043-57 (2015). WB . PubMed: 26343374
  • Liu Y  et al. The role of von Willebrand factor as a biomarker of tumor development in hepatitis B virus-associated human hepatocellular carcinoma: a quantitative proteomic based study. J Proteomics 106:99-112 (2014). WB ; Human . PubMed: 24769235
  • Wu J  et al. EGFR-STAT3 signaling promotes formation of malignant peripheral nerve sheath tumors. Oncogene 33:173-80 (2014). IHC ; Mouse . PubMed: 23318430
  • Turkington RC  et al. Fibroblast growth factor receptor 4 (FGFR4): a targetable regulator of drug resistance in colorectal cancer. Cell Death Dis 5:e1046 (2014). WB ; Human . PubMed: 24503538
  • Tsai AC  et al. Orally active microtubule-targeting agent, MPT0B271, for the treatment of human non-small cell lung cancer, alone and in combination with erlotinib. Cell Death Dis 5:e1162 (2014). Human . PubMed: 24722287
  • Peng Y & Zhang L Activation of the TLR1/2 pathway induces the shaping of the immune response status of peripheral blood leukocytes. Exp Ther Med 7:1708-1712 (2014). WB ; Human . PubMed: 24926371
  • Zheng P  et al. Regulation of signal transducer and activator of transcription 3 and apoptotic pathways by betaine attenuates isoproterenol-induced acute myocardial injury in rats. Hum Exp Toxicol N/A:N/A (2014). Rat . PubMed: 25080425
  • Chen RY  et al. Effect of oridonin-mediated hallmark changes on inflammatory pathways in human pancreatic cancer (BxPC-3) cells. World J Gastroenterol 20:14895-903 (2014). WB ; Human . PubMed: 25356049
  • Tai WT  et al. STAT3 mediates regorafenib-induced apoptosis in hepatocellular carcinoma. Clin Cancer Res 20:5768-76 (2014). PubMed: 25248379
  • Brisslert M  et al. S100A4 regulates the Src-tyrosine kinase dependent differentiation of Th17 cells in rheumatoid arthritis. Biochim Biophys Acta 1842:2049-59 (2014). WB, IHC-P ; Mouse . PubMed: 25035294
  • Pathak RR  et al. Loss of phosphatase and tensin homolog (PTEN) induces leptin-mediated leptin gene expression: feed-forward loop operating in the lung. J Biol Chem 288:29821-35 (2013). WB ; Human . PubMed: 23963458
  • Chai S  et al. Ca(2+)/calmodulin-dependent protein kinase II?, a critical mediator of the NF-?B network, is a novel therapeutic target in non-small cell lung cancer. Cancer Lett N/A:N/A (2013). Human . PubMed: 24189456
  • Szelag M  et al. In silico simulations of STAT1 and STAT3 inhibitors predict SH2 domain cross-binding specificity. Eur J Pharmacol 720:38-48 (2013). Human . PubMed: 24211327
  • Bao W  et al. A TrkB-STAT3-miR-204-5p regulatory circuitry controls proliferation and invasion of endometrial carcinoma cells. Mol Cancer 12:155 (2013). WB, IHC-P ; Human . PubMed: 24321270
  • Qu Y  et al. Generation of prostate tumor-initiating cells is associated with elevation of reactive oxygen species and IL-6/STAT3 signaling. Cancer Res 73:7090-100 (2013). WB ; Human . PubMed: 24101153
  • Feldman DE  et al. Pluripotency factor-mediated expression of the leptin receptor (OB-R) links obesity to oncogenesis through tumor-initiating stem cells. Proc Natl Acad Sci U S A 109:829-34 (2012). WB ; Mouse . PubMed: 22207628
  • Liu DB  et al. Celecoxib induces apoptosis and cell-cycle arrest in nasopharyngeal carcinoma cell lines via inhibition of STAT3 phosphorylation. Acta Pharmacol Sin 33:682-90 (2012). Human . PubMed: 22504904
  • Wang HZ  et al. Hepcidin is regulated during blood-stage malaria and plays a protective role in malaria infection. J Immunol 187:6410-6 (2011). PubMed: 22084434
  • Chen CF  et al. Establishment of a transgenic zebrafish line for superficial skin ablation and functional validation of apoptosis modulators in vivo. PLoS One 6:e20654 (2011). WB . PubMed: 21655190
  • Marroquí L  et al. Leptin downregulates expression of the gene encoding glucagon in alphaTC1-9 cells and mouse islets. Diabetologia 54:843-51 (2011). PubMed: 21234744
  • Desai M  et al. Programmed hyperphagia due to reduced anorexigenic mechanisms in intrauterine growth-restricted offspring. Reprod Sci 14:329-37 (2007). PubMed: 17644805


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