Overview

  • Product nameAnti-STAT4 antibody
    See all STAT4 primary antibodies
  • Description
    Rabbit polyclonal to STAT4
  • SpecificityDetects endogenous levels of total STAT4 protein.
  • Tested applicationsSuitable for: ELISA, WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic non-phosphopeptide derived from human STAT4 around the phosphorylation site of Tyrosine 693 (KGYVP)

  • Positive control
    • Extracts from RAW264.7 cells treated with EGF (200 ng/ml for 5 mins); human breast carcinoma tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab55357 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/40000.
WB 1/500 - 1/1000. Detects a band of approximately 86 kDa (predicted molecular weight: 86 kDa).
IHC-P Use at an assay dependent concentration.

Target

  • FunctionCarries out a dual function: signal transduction and activation of transcription. Involved in IL12 signaling.
  • Involvement in diseaseSystemic lupus erythematosus 11
    Rheumatoid arthritis
  • Sequence similaritiesBelongs to the transcription factor STAT family.
    Contains 1 SH2 domain.
  • Post-translational
    modifications
    Tyrosine phosphorylated. Serine phosphorylation is also required for maximal transcriptional activity.
  • Cellular localizationCytoplasm. Nucleus. Translocated into the nucleus in response to phosphorylation.
  • Information by UniProt
  • Database links
  • Alternative names
    • Signal transducer and activator of transcription 4 antibody
    • SLEB11 antibody
    • STAT4 antibody
    • STAT4_HUMAN antibody

Anti-STAT4 antibody images

  • Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using ab55357 at 1/50 dilution. Left: without immunizing peptide; Right: with immunizing peptide
  • All lanes : Anti-STAT4 antibody (ab55357) at 1/500 dilution

    Lane 1 : extracts from RAW264.7 cells treated with EGF (200 ng/ml for 5 mins) with immunizing peptide
    Lane 2 : extracts from RAW264.7 cells treated with EGF (200 ng/ml for 5 mins)


    Predicted band size : 86 kDa
    Observed band size : 86 kDa

References for Anti-STAT4 antibody (ab55357)

ab55357 has not yet been referenced specifically in any publications.

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