General notesab94123 is a 293T cell transfected lysate in which Human STAT4 has been transiently over-expressed using a pCMV-STAT4 plasmid. The lysate is provided in 1X Sample Buffer.
Note: For more details about how the transfected lysate was prepared view preparation notes
BackgroundDisease: Systemic lupus erythematosus 11
Function: Carries out a dual function: signal transduction and activation of transcription. Involved in IL12 signaling.
PTM: Tyrosine phosphorylated. Serine phosphorylation is also required for maximal transcriptional activity.
Similarity: Belongs to the transcription factor STAT family.
Contains 1 SH2 domain.