Anti-STATIP1 antibody (ab18048)

Overview

  • Product name
  • Description
    Rabbit polyclonal to STATIP1
  • Specificity
    Specific for StIP-1 at 92kDa, which may appear as a doublet. Also recognizes a second band at ~70kDa.
  • Tested applications
    Suitable for: IP, WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide:

    CSPDSKYFFTGSRDKK

    conjugated to KLH, corresponding to Internal sequence amino acids 679 - 693 of Mouse StIp-1.

  • Positive control
    • BAF-3 RIPA cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab18048 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP
WB
  • Application notes
    IP: Use at 1 - 4µg/0.5mg of lysate.
    WB: Use at a concentration of 1 µg/ml. Detects a band of approximately 92 kDa (predicted molecular weight: 63 kDa).

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Regulates the ligand-dependent activation of STAT3.
      Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4.
    • Sequence similarities
      Belongs to the WD repeat ELP2 family.
      Contains 14 WD repeats.
    • Cellular localization
      Cytoplasm. Nucleus.
    • Information by UniProt
    • Database links
    • Alternative names
      • AU023723 antibody
      • Elongation protein 2 homolog (S. cerevisiae) antibody
      • Elongator acetyltransferase complex subunit 2 antibody
      • Elongator complex protein 2 antibody
      • elongator protein 2 antibody
      • ELP2 antibody
      • ELP2_HUMAN antibody
      • Epl2 antibody
      • FLJ10879 antibody
      • SHINC 2 antibody
      • SHINC-2 antibody
      • SHINC2 antibody
      • signal transducer and activator of transcription 3 interacting protein 1 antibody
      • signal transducer and activator of transcription interacting protein 1 antibody
      • STAT3 interacting protein 1 antibody
      • Stat3 interacting protein antibody
      • STAT3-interacting protein 1 antibody
      • STATIP 1 antibody
      • STATIP1 antibody
      • STATIP1 protein antibody
      • StIP antibody
      • StIP1 antibody
      see all

    References

    ab18048 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

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    Abcam guarantees this product to work in the species/application used in this Abreview.
    Application
    Western blot
    Sample
    Human Cell lysate - whole cell (Lung)
    Loading amount
    20 µg
    Specification
    Lung
    Gel Running Conditions
    Reduced Denaturing (8%)
    Blocking step
    Milk as blocking agent for 2 hour(s) and 0 minute(s) · Concentration: 10%
    Username

    Abcam user community

    Verified customer

    Submitted Jul 01 2009

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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