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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Concentration information loading... Preparation and Storage
Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.02% Sodium azide
Constituent: 0.1% BSA
Double stranded RNA binding protein Staufen homolog
Double stranded RNA binding protein Staufen homolog 1
Double-stranded RNA-binding protein Staufen homolog 1
Function Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site.
Tissue specificity Widely expressed. Expressed in brain, pancreas, heart, skeletal muscles, liver, lung, kidney and placenta.
Sequence similarities Contains 3 DRBM (double-stranded RNA-binding) domains.
Domain One of the DRDB could be involved in RER binding. The C-terminal contains the tubulin binding domain (TBD).
Cellular localization Cytoplasm. Rough endoplasmic reticulum. Localizes exclusively with the rough reticulum endoplasmic.
Information by UniProt
References for Staufen peptide (ab110446)
has not yet been referenced specifically in any publications.
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