Overview

Description

  • NatureSynthetic

Specifications

Our Abpromise guarantee covers the use of ab110446 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking

  • FormLiquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

    Preservative: 0.02% Sodium azide
    Constituent: 0.1% BSA

General Info

  • Alternative names
    • Double stranded RNA binding protein Staufen homolog
    • Double stranded RNA binding protein Staufen homolog 1
    • Double-stranded RNA-binding protein Staufen homolog 1
    • FLJ25010
    • MGC124588
    • STAU
    • STAU1
    • STAU1_HUMAN
    • staufen
    • Staufen RNA binding protein (Drosophila)
    • Staufen RNA binding protein homolog 1
    • Staufen, RNA binding protein, homolog 1 (Drosophila)
    see all
  • FunctionBinds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site.
  • Tissue specificityWidely expressed. Expressed in brain, pancreas, heart, skeletal muscles, liver, lung, kidney and placenta.
  • Sequence similaritiesContains 3 DRBM (double-stranded RNA-binding) domains.
  • DomainOne of the DRDB could be involved in RER binding.
    The C-terminal contains the tubulin binding domain (TBD).
  • Cellular localizationCytoplasm. Rough endoplasmic reticulum. Localizes exclusively with the rough reticulum endoplasmic.
  • Information by UniProt

References for Staufen peptide (ab110446)

ab110446 has not yet been referenced specifically in any publications.

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