Overview

  • Product nameStauprimide
  • Description
    Stem cell differentiation primer. Staurosporine analog.
  • Biological descriptionPrimes embryonic stem cells (ESCs) for efficient differentiation. Potently increases Sox17+/Sox7- cell differentiation from ESCs (EC50 = 0.3 μM). Downregulates c-Myc expression by inhibiting nucleoside diphosphate kinase B (NME2) nuclear localization. Staurosporine (ab120056) analog.
  • Purity> 99%

Properties

  • Chemical nameN-[(9S,10R,11R,13R)-2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-1,3-dioxo-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]-benzodiazonin-11-yl]-N-methylbenzamide
  • Molecular weight584.63
  • Chemical structureChemical Structure
  • Molecular formulaC35H28N4O5
  • CAS Number154589-96-5
  • PubChem identifier46245328
  • Storage instructionsStore at -20°C. Store at -20°C long term. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under Desiccating conditions.
  • Solubility overviewSoluble in DMSO to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILESO=C(c1ccccc1)N(C)[C@@H]2C[C@H]9O[C@@](C)([C@@H]2OC)n5c4c3n9c8ccccc8c3c7c(c4c6ccccc56)C(=O)NC7=O
  • Source

    Synthetic

  • Research areas

    References for Stauprimide (ab120978)

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