Overview

  • Product nameAnti-STEAP1 antibody
    See all STEAP1 primary antibodies
  • Description
    Rabbit polyclonal to STEAP1
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Cow, Monkey
  • Immunogen

    Synthetic peptide conjugated to KLH, from the N terminal of Human STEAP1 (NP_036581.1).

  • Positive control
    • Human Prostate tissues.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab117257 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 2 µg/ml. Predicted molecular weight: 40 kDa.
IHC-P Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionMetalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor.
  • Tissue specificityUbiquitously expressed. Highly expressed in prostate tumors.
  • Sequence similaritiesBelongs to the STEAP family.
    Contains 1 ferric oxidoreductase domain.
  • Cellular localizationEndosome membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 2410007B19Rik antibody
    • EC 1.16.1.- antibody
    • Metalloreductase STEAP1 antibody
    • MGC19484 antibody
    • PRSS 24 antibody
    • PRSS24 antibody
    • Six transmembrane epithelial antigen of prostate antibody
    • Six transmembrane epithelial antigen of the prostate 1 antibody
    • Six transmembrane epithelial antigen of the prostate antibody
    • Six-transmembrane epithelial antigen of prostate 1 antibody
    • STEA1_HUMAN antibody
    • STEAP 1 antibody
    • Steap antibody
    • STEAP1 antibody
    see all

Anti-STEAP1 antibody images

  • ab115257, at 10 µg/ml, staining STEAP1 in Formalin-fixed, Paraffin-embedded Human Prostate tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

References for Anti-STEAP1 antibody (ab117257)

ab117257 has not yet been referenced specifically in any publications.

Product Wall

Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Sample Human Tissue sections (Prostate Cancer)
Antigen retrieval step Heat mediated - Buffer/Enzyme Used: Citrate buffer pH 6.0
Permeabilization No
Specification Prostate Cancer
Blocking step Serum as blocking agent for 15 minute(s) · Concentration: 10% · Temperature: RT°C
Fixative Formaldehyde
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Submitted Nov 13 2015

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"