Overview

  • Product nameAnti-STEAP4 antibody
    See all STEAP4 primary antibodies
  • Description
    Goat polyclonal to STEAP4
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Dog
  • Immunogen

    Synthetic peptide:

    CVDNTLTRIRQGWERN

    , corresponding to C terminal amino acids 441-456 of Human STEAP4

  • Positive control
    • Human Adipose lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab63967 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesPeptide ELISA: antibody detection limit dilution: 1/4000.
    WB: Use at a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 52 kDa (predicted molecular weight: 52 kDa).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionMetalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor. Play a role in systemic metabolic homeostasis, integrating inflammatory and metabolic responses (By similarity). Associated with obesity and insulin-resistance. Involved in inflammatory arthritis, through the regulation of inflammatory cytokines. Inhibits anchorage-independent cell proliferation.
    • Tissue specificityUbiquitous. Highly expressed in adipose tissue. Expressed in placenta, lung, heart and prostate. Detected at lower levels in liver, skeletal muscle, pancreas, testis and small intestine. Highly expressed in joints of patients with rheumatoid arthritis and localized with CD68 cells, a marker for macrophages.
    • Sequence similaritiesBelongs to the STEAP family.
      Contains 1 ferric oxidoreductase domain.
    • Cellular localizationCell membrane. Golgi apparatus membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • alpha-induced protein 9 antibody
      • Metalloreductase STEAP4 antibody
      • six transmembrane prostate protein 2 antibody
      • Six-transmembrane epithelial antigen of prostate 4 antibody
      • SixTransMembrane protein of prostate 2 antibody
      • STAMP 2 antibody
      • STAMP2 antibody
      • STEA4_HUMAN antibody
      • STEAP 4 antibody
      • STEAP family member 4 antibody
      • STEAP4 antibody
      • TIARP antibody
      • TNFAIP 9 antibody
      • TNFAIP9 antibody
      • Tumor necrosis factor antibody
      • tumor necrosis factor, alpha-induced protein 9 antibody
      • tumor necrosis-alpha-induced adipose-related protein antibody
      see all

    Anti-STEAP4 antibody images

    • Anti-STEAP4 antibody (ab63967) at 0.3 µg/ml + Human Adipose lysate at 35 µg

      Predicted band size : 52 kDa
      Observed band size : 52 kDa

    References for Anti-STEAP4 antibody (ab63967)

    ab63967 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab63967.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"