Overview

  • Product nameAnti-Steroid sulfatase antibody
    See all Steroid sulfatase primary antibodies
  • Description
    Rabbit polyclonal to Steroid sulfatase
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 487-517 of Human Steroid sulfatase

  • Positive control
    • Hela cell line lysates

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • Storage bufferPreservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesPurified through a protein A column, followed by peptide affinity purification
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab123259 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 65 kDa.

Target

  • FunctionConversion of sulfated steroid precursors to estrogens during pregnancy.
  • Involvement in diseaseDefects in STS are the cause of ichthyosis X-linked (IXL) [MIM:308100]. Ichthyosis X-linked is a keratinization disorder manifesting with mild erythroderma and generalized exfoliation of the skin within a few weeks after birth. Affected boys later develop large, polygonal, dark brown scales, especially on the neck, extremities, trunk, and buttocks.
  • Sequence similaritiesBelongs to the sulfatase family.
  • Post-translational
    modifications
    The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.
  • Cellular localizationEndoplasmic reticulum membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • ARSC antibody
    • ARSC1 antibody
    • Arylsulfatase C antibody
    • Arylsulfatase C isozyme S antibody
    • ASC antibody
    • EC 3.1.6.2 antibody
    • ES antibody
    • Estrone sulfatase antibody
    • SSDD antibody
    • Steroid sulfatase (microsomal) antibody
    • Steroid sulfatase (microsomal) arylsulfatase C isozyme S antibody
    • Steroid sulfatase antibody
    • Steryl sulfatase antibody
    • Steryl sulfatase precursor antibody
    • Steryl sulfate sulfohydrolase antibody
    • Steryl-sulfatase antibody
    • Steryl-sulfate sulfohydrolase antibody
    • STS antibody
    • STS_HUMAN antibody
    see all

Anti-Steroid sulfatase antibody images

  • Anti-Steroid sulfatase antibody (ab123259) at 1/100 dilution + Hela cell line lysates at 35 µg

    Predicted band size : 65 kDa

References for Anti-Steroid sulfatase antibody (ab123259)

ab123259 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"