Overview

  • Product nameAnti-Steroid sulfatase antibody
    See all Steroid sulfatase primary antibodies
  • Description
    Goat polyclonal to Steroid sulfatase
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Cynomolgus Monkey
  • Immunogen

    Synthetic peptide:

    QAGQKIDEPTSN

    , corresponding to internal sequence amino acids 389-400 of Human Steroid sulfatase

  • Positive control
    • Human Placenta lysate.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris saline, pH 7.3
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesPurified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab65094 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
  • Application notesPeptide ELISA: antibody detection limit dilution 1:32,000.
    WB: Use at a concentration of 0.01 - 0.03 µg/ml. Detects a band of approximately 70 kDa (predicted molecular weight: 66 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionConversion of sulfated steroid precursors to estrogens during pregnancy.
    • Involvement in diseaseDefects in STS are the cause of ichthyosis X-linked (IXL) [MIM:308100]. Ichthyosis X-linked is a keratinization disorder manifesting with mild erythroderma and generalized exfoliation of the skin within a few weeks after birth. Affected boys later develop large, polygonal, dark brown scales, especially on the neck, extremities, trunk, and buttocks.
    • Sequence similaritiesBelongs to the sulfatase family.
    • Post-translational
      modifications
      The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.
    • Cellular localizationEndoplasmic reticulum membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • ARSC antibody
      • ARSC1 antibody
      • Arylsulfatase C antibody
      • Arylsulfatase C isozyme S antibody
      • ASC antibody
      • EC 3.1.6.2 antibody
      • ES antibody
      • Estrone sulfatase antibody
      • SSDD antibody
      • Steroid sulfatase (microsomal) antibody
      • Steroid sulfatase (microsomal) arylsulfatase C isozyme S antibody
      • Steroid sulfatase antibody
      • Steryl sulfatase antibody
      • Steryl sulfatase precursor antibody
      • Steryl sulfate sulfohydrolase antibody
      • Steryl-sulfatase antibody
      • Steryl-sulfate sulfohydrolase antibody
      • STS antibody
      • STS_HUMAN antibody
      see all

    Anti-Steroid sulfatase antibody images

    References for Anti-Steroid sulfatase antibody (ab65094)

    ab65094 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab65094.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"