Anti-Sterol carrier protein 2 antibody (ab93175)

Overview

  • Product name
    Anti-Sterol carrier protein 2 antibody
    See all Sterol carrier protein 2 primary antibodies
  • Description
    Rabbit polyclonal to Sterol carrier protein 2
  • Tested applications
    Suitable for: WB, IHC-P, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    KLH conjugated synthetic peptide selected from the central region of Human SCP2.

  • Positive control
    • A2058 cell line lysates. Human hepatocarcinoma tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab93175 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
IHC-P
ELISA
  • Application notes
    ELISA: Use at an assay dependent dilution.
    IHC-P: Use at an assay dependent dilution.
    WB: 1/100 - 1/500. Predicted molecular weight: 175 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Mediates in vitro the transfer of all common phospholipids, cholesterol and gangliosides between membranes. May play a role in regulating steroidogenesis.
    • Tissue specificity
      Liver, fibroblasts, and placenta.
    • Involvement in disease
      Defects in SCP2 are a cause of leukoencephalopathy with dystonia and motor neuropathy (LDMN) [MIM:613724]; also known as sterol carrier protein 2 deficiency. LDMN is a syndrome characterized by leukoencephalopathy, dystonic head tremor, spasmodic torticollis and reduced tendon reflexes in lower extremities. Additional features include hyposmia, pathologic saccadic eye movements, a slight hypoacusis, accumulation of branched-chain pristanic acid in plasma, and the presence of abnormal bile alcohol glucuronides in urine.
    • Sequence similarities
      In the N-terminal section; belongs to the thiolase family.
      Contains 1 SCP2 domain.
    • Cellular localization
      Mitochondrion; Cytoplasm. Mitochondrion. Cytoplasmic in the liver and also associated with mitochondria especially in steroidogenic tissues and Peroxisome. Interaction with PEX5 is essential for peroxisomal import.
    • Information by UniProt
    • Database links
    • Alternative names
      • DKFZp686C12188 antibody
      • DKFZp686D11188 antibody
      • NLTP antibody
      • NLTP_HUMAN antibody
      • Non-specific lipid-transfer protein antibody
      • Nonspecific lipid transfer protein antibody
      • NSL TP antibody
      • NSL-TP antibody
      • OTTHUMP00000010488 antibody
      • OTTHUMP00000231766 antibody
      • OTTHUMP00000231767 antibody
      • OTTHUMP00000231768 antibody
      • OTTHUMP00000231769 antibody
      • OTTHUMP00000231770 antibody
      • OTTHUMP00000231772 antibody
      • OTTHUMP00000231773 antibody
      • OTTHUMP00000231774 antibody
      • OTTHUMP00000231776 antibody
      • OTTHUMP00000234662 antibody
      • Propanoyl CoA C acyltransferase antibody
      • Propanoyl-CoA C-acyltransferase antibody
      • SCP 2 antibody
      • SCP chi antibody
      • SCP X antibody
      • SCP-2 antibody
      • SCP-chi antibody
      • SCP-X antibody
      • SCP2 antibody
      • SCPchi antibody
      • SCPX antibody
      • Sterol carrier protein 2 antibody
      • Sterol carrier protein X antibody
      see all

    Images

    • Anti-Sterol carrier protein 2 antibody (ab93175) at 1/100 dilution + A2058 cell line lysates at 35 µg

      Predicted band size : 175 kDa
    • Formalin-fixed and paraffin-embedded Human hepatocarcinoma reacted with ab93175, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

    References

    ab93175 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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