The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1000. Predicted molecular weight: 21 kDa.
FunctionIs a key regulator of neurite extension through regulation of microtubule instabilily.
Tissue specificityNeuron specific.
Sequence similaritiesBelongs to the stathmin family.
Cellular localizationCytoplasm. Cytoplasm > perinuclear region. Cell projection > growth cone. Membrane. Cell projection > axon. Associated with punctate structures in the perinuclear cytoplasm, axons, and growth cones of developing neurons. SCG10 exists in both soluble and membrane-bound forms.