Mouse monoclonal [504.5] to Streptococcus agalactiae
SpecificityThis antibody cross-reacts weakly with Strep. dysgalactiae.
Does not cross-react with Strep. uberis, Strep. bovis, Strep. faecalis, Staph. aureus, Mycoplasma bovis, Mycoplasma californicum, Mycoplasma bovigenitalium, E. coli or Corynebacterium bovis.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notesELISA: 1/1,024,00.
ELISA is an indirect assay against Strep. agalactiae cells on the solid phase. Titers represent endpoint dilutions that achieve absorbance values > 0.1.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
RelevanceOnce thought to infect only cows, where it produces mastitis, Streptococcus agalactiae is now known to be able to cause serious disease, bacteremia and meningitis, in immunocompromised individuals and in neonates. Infections in the newborn are the most common and are extremely serious. They are of two types. Early onset of infection, usually occuring within 5 days of birth, is manifested by bacteremia and pneumonia. This infection is contracted vertically, as the baby passes through the birth canal. The other type of infection is a meningitis that occurs between the 10th and 60th days of life. The origin of this infection is not known, but it is not believed to be the mother.
References for Anti-Streptococcus agalactiae antibody [504.5] (ab41203)
This product has been referenced in:
Pazos-Perez N et al. Ultrasensitive multiplex optical quantification of bacteria in large samples of biofluids. Sci Rep6:29014 (2016).
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