Recombinant S. pyogenes Streptolysin O (Hemolytic streptococcus) protein (ab126650)
Key features and details
- Expression system: Escherichia coli
- Suitable for: SDS-PAGE
Description
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Product name
Recombinant S. pyogenes Streptolysin O (Hemolytic streptococcus) protein
See all Streptolysin O (Hemolytic streptococcus) proteins and peptides -
Expression system
Escherichia coli -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Streptococcus pyogenes -
Sequence
MSNKKTFKKY SRVAGLLTAA LIIGNLVTAN AESNKQNTAS TETTTTNEQP KPESSELTTE KAGQKTDDML NSNDMIKLAP KEMPLESAEK EEKKSEDKKK SEEDHTEEIN DKIYSLNYNE LEVLAKNGET IENFVPKEGV KKADKFIVIE RKKKNINTTP VDISIIDSVT DRTYPAALQL ANKGFTENKP DAVVTKRNPQ KIHIDLPGMG DKATVEVNDP TYANVSTAID NLVNQWHDNY SGGNTLPART QYTESMVYSK SQIEAALNVN SKILDGTLGI DFKSISKGEK KVMIAAYKQI FYTVSANLPN NPADVFDKSV TFKELQRKGV SNEAPPLFVS NVAYGRTVFV KLETSSKSND VEAAFSAALK GTDVKTNGKY SDILENSSFT AVVLGGDAAE HNKVVTKDFD VIRNVIKDNA TFSRKNPAYP ISYTSVFLKN NKIAGVNNRT EYVETTSTEY TSGKINLSHR GAYVAQYEIL WDEINYDDKG KEVITKRRWD NNWYSKTSPF STVIPLGANS RNIRIMAREC TGLAWEWWRK VIDERDVKLS KEINVNISGS TLSPYGSITY K -
Predicted molecular weight
64 kDa -
Amino acids
1 to 571
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Description
Recombinant S. pyogenes Streptolysin O (Hemolytic streptococcus) protein
Specifications
Our Abpromise guarantee covers the use of ab126650 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
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Form
Liquid -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.09% Sodium azide
Constituents: 0.88% Sodium chloride, 0.32% Tris HCl
General Info
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Alternative names
- Streptolysin O
- Streptolysin O (Thiol-activated cytolysin) slo
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Relevance
Streptolysin O (SLO) is a membrane-damaging extracellular toxin produced by hemolytic streptococci. The membrane-damaging activity is measured by hemolysis of red-blood cell. SLO is oxygen-sensitive and is easily inactivated in its presence but can be reactivated by thiol compounds , so it is also called thiol-activated cytolysin. SLO is produced not only by Group A hemolytic streptococci but also by Group C and Group G strains. The amino acid sequences are highly conserved among them and their homology is over 98%.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab126650 has been referenced in 1 publication.
- Wang Y et al. NAD+ supplement potentiates tumor-killing function by rescuing defective TUB-mediated NAMPT transcription in tumor-infiltrated T cells. Cell Rep 36:109516 (2021). PubMed: 34380043