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Rabbit polyclonal to Sts1
Recombinant fragment, corresponding to a region within amino acids 117-649 of Human Sts1.
Jurkat and THP-1 whole cell lysates; Human hepatoma tissue.
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Preservative: 0.01% Thimerosal (merthiolate) Constituents: 79% PBS, 20% Glycerol
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Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1000 - 1/10000. Predicted molecular weight: 73 kDa.
1/100 - 1/1000.
Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors and EGFR, on the cell surface. Exhibits tyrosine phosphatase activity toward several substrates including EGFR, FAK, SYK, and ZAP70. Down-regulates proteins that are dually modified by both protein tyrosine phosphorylation and ubiquitination.
Contains 1 SH3 domain.
Contains 1 UBA domain.
Information by UniProt
Cbl interacting protein p70 antibody
Cbl interacting protein Sts 1 antibody
Cbl interacting protein Sts1 antibody
Western blot - Anti-Sts1 antibody (ab155307)
All lanes : Anti-Sts1 antibody (ab155307) at 1/5000 dilution Lane 1 : Jurkat whole cell lysate Lane 2 : THP-1 whole cell lysate Lysates/proteins at 30 µg per lane. Predicted band size : 73 kDa
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Sts1 antibody (ab155307)
Immunohistochemical analysis of paraffin-embedded Human hepatoma tissue, labeling Sts1 with ab155307 at 1/500 dilution.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"