Overview

  • Product name
    Anti-STT3B antibody
  • Description
    Rabbit polyclonal to STT3B
  • Tested applications
    Suitable for: IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    antigen sequence: NPPVEDSSDE DDKRNQGNLY DKAGKVRKHA TEQEKTEEGL GP, corresponding to amino acids 492-533 of Human STT3B.

  • Positive control
    • Human testis tissue; Human A-431 cell line.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab122351 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/600. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC/IF Use a concentration of 1 - 4 µg/ml. Fixation/Permeabilization: PFA/Triton X-100

Target

  • Function
    Component of the N-oligosaccharyl transferase enzyme which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). SST3B seems to be involved in complex substrate specificity.
  • Tissue specificity
    Expressed in heart, brain, placenta, lung, liver, muscle, kidney and pancreas. Expressed in skin fibroblasts (at protein level).
  • Sequence similarities
    Belongs to the STT3 family.
  • Cellular localization
    Endoplasmic reticulum membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B antibody
    • Homolog of yeast STT3 antibody
    • Oligosaccharyl transferase subunit STT3B antibody
    • SIMP antibody
    • source of immunodominant MHC associated peptides antibody
    • Source of immunodominant MHC-associated peptides homolog antibody
    • STT3 subunit of the oligosaccharyltransferase complex homolog B (S. cerevisiae) antibody
    • STT3 subunit of the oligosaccharyltransferase complex homolog B antibody
    • STT3-B antibody
    • Stt3b antibody
    • STT3B_HUMAN antibody
    see all

Images

  • ab122351, at 1/600 dilution, staining STT3B in paraffin-embedded Human testis tissue by Immunohistochemistry.
  • ab122351, at 4 µg/ml, staining STT3B in Human cell line A-431 by Immunofluorescence. Antibody staining is shown in green.

References

ab122351 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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