Overview

  • Product name
  • Description
    Mouse polyclonal to STYX
  • Specificity
    This antibody is reactive against mammalian transfected lysate.
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    STYX (NP_660294.1, 1 a.a. ~ 223 a.a) full-length human protein.

  • Positive control
    • STYX transfected 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab68016 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 25 kDa (predicted molecular weight: 25 kDa).

Target

  • Function
    Probable pseudophosphatase. Contains a Gly residue instead of a conserved Cys residue in the dsPTPase catalytic loop which renders it catalytically inactive as a phosphatase. The binding pocket is however sufficiently preserved to bind phosphorylated substrates, and maybe protect them from phosphatases. Seems to play a role in spermiogenesis.
  • Sequence similarities
    Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
    Contains 1 tyrosine-protein phosphatase domain.
  • Information by UniProt
  • Database links
  • Alternative names
    • Protein tyrosine phosphatase like protein antibody
    • Protein tyrosine phosphatase-like protein antibody
    • Serine/threonine/tyrosine interacting protein antibody
    • Serine/threonine/tyrosine-interacting protein antibody
    • Styx antibody
    • STYX_HUMAN antibody
    see all

Images

  • All lanes : Anti-STYX antibody (ab68016) at 1/500 dilution

    Lane 1 : STYX transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

    Predicted band size : 25 kDa
    Observed band size : 25 kDa

References

This product has been referenced in:
  • Reiterer V  et al. Pseudophosphatase STYX modulates cell-fate decisions and cell migration by spatiotemporal regulation of ERK1/2. Proc Natl Acad Sci U S A 110:E2934-43 (2013). Read more (PubMed: 23847209) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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