Overview

  • Product name
    Anti-Substance P antibody [NC1/34]
    See all Substance P primary antibodies
  • Description
    Rat monoclonal [NC1/34] to Substance P
  • Specificity
    ab150349 recognizes COOH-terminal end of substance P. It doesn’t recognize Leu- or Met-enkephalin, somatostatin or beta-endorphin. Cross reactivity with eledoisin: 5%.
  • Tested applications
    Suitable for: IHC-Fr, ICCmore details
  • Species reactivity
    Reacts with: Pigeon, Crab
    Predicted to work with: Mammal
  • Immunogen

    Substance P conjugated to BSA

Properties

Applications

Our Abpromise guarantee covers the use of ab150349 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr Use at an assay dependent concentration.
ICC 1/200.

Target

  • Function
    Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.
  • Sequence similarities
    Belongs to the tachykinin family.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Alternative names
    • C-terminal-flanking peptide antibody
    • Hs.2563 antibody
    • neurokinin 1 antibody
    • neurokinin 2 antibody
    • neurokinin A antibody
    • neurokinin alpha antibody
    • Neuromedin L antibody
    • neuropeptide gamma antibody
    • neuropeptide K antibody
    • NK2 antibody
    • NKA antibody
    • NKNA antibody
    • NPK antibody
    • PPT antibody
    • preprotachykinin antibody
    • protachykinin antibody
    • protachykinin-1 antibody
    • Substance K antibody
    • SubstanceP antibody
    • TAC1 antibody
    • TAC2 antibody
    • TAC2, formerly antibody
    • Tachykinin 1 antibody
    • tachykinin 2 antibody
    • tachykinin 2, formerly antibody
    • Tachykinin precursor 1 antibody
    • tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma) antibody
    • Tachykinin1 antibody
    • TKN1_HUMAN antibody
    see all

References

This product has been referenced in:
  • Cuello AC  et al. Detection of substance P in the central nervous system by a monoclonal antibody. Proc Natl Acad Sci U S A 76:3532-6 (1979). Read more (PubMed: 386341) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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